SAMe Side Effects
Generic Name: s-adenosylmethionine
Note: This document contains side effect information about s-adenosylmethionine. Some of the dosage forms listed on this page may not apply to the brand name SAMe.
Applies to s-adenosylmethionine: oral tablet
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Although not all side effects are known, SAMe is thought to be likely safe for most adults.
Common side effects may include:
feeling anxious or nervous;
vomiting, upset stomach;
increased sweating; or
sleep problems (insomnia).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Some side effects may not be reported. You may report them to the FDA.