Skip to Content

Riopan Plus 2 Side Effects

Generic Name: magaldrate / simethicone

Note: This document contains side effect information about magaldrate / simethicone. Some of the dosage forms listed on this page may not apply to the brand name Riopan Plus 2.

Applies to magaldrate / simethicone: oral suspension, oral tablet chewable


Musculoskeletal side effects including osteomalacia, bone pain, and muscular weakness have been reported with the use of magaldrate.[Ref]


Other side effects have been reported with the use of magaldrate including malaise, decreased fluoride absorption, milk-alkali syndrome, and aluminum accumulation in serum, bone and the CNS.[Ref]

Nervous system

Nervous system side effects including neurotoxicity and encephalopathy have been reported with the use of magaldrate.[Ref]


Gastrointestinal side effects including rebound hyperacidity, diarrhea, intestinal obstruction, and constipation have been reported with the use of magaldrate.[Ref]


Simethicone has no known side effects.[Ref]


1. "Product Information. Ron Acid (magaldrate)." Major Pharmaceuticals Inc, Livonia, MI.

2. "Product Information. Mylicon (simethicone)." Johnson and Johnson Medical Inc, Arlington, TX.

Some side effects of Riopan Plus 2 may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

More about Riopan Plus 2 (magaldrate / simethicone)

Related treatment guides

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.