Relyvrio Side Effects

Generic name: sodium phenylbutyrate / taurursodiol

Medically reviewed by Drugs.com. Last updated on Sep 15, 2023.

Note: This document contains side effect information about sodium phenylbutyrate / taurursodiol. Some dosage forms listed on this page may not apply to the brand name Relyvrio.

Applies to sodium phenylbutyrate / taurursodiol: oral powder for suspension.

Serious side effects of Relyvrio

Along with its needed effects, sodium phenylbutyrate/taurursodiol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking sodium phenylbutyrate / taurursodiol:

More common

Diarrhea
nausea
stomach pain

Other side effects of Relyvrio

Some side effects of sodium phenylbutyrate / taurursodiol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Body aches or pain
chills
cough
ear congestion
fever
headache
loss of voice
sneezing
sore throat
stuffy or runny nose
trouble breathing
unusual tiredness or weakness

For Healthcare Professionals

Applies to sodium phenylbutyrate / taurursodiol: oral powder for reconstitution.

Gastrointestinal

Very common (10% or more): Abdominal pain (21%), diarrhea (25%), nausea (18%), salivary hypersecretion (11%)^[Ref]

General

The most common adverse reactions were diarrhea, abdominal pain, nausea, and upper respiratory tract infection. While gastrointestinal side effects occurred throughout the study duration, they were more common in the first three weeks of treatment.^[Ref]