Rabies Immune Globulin, Human Side Effects

Medically reviewed by Drugs.com. Last updated on Aug 22, 2024.

Applies to rabies immune globulin, human: intramuscular solution.

Serious side effects

Along with its needed effects, rabies immune globulin, human may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking rabies immune globulin, human:

More common side effects

• body aches or pain
• chills
• cough
• difficulty in breathing
• ear congestion
• fever
• headache
• loss of voice
• nasal congestion
• runny nose
• sneezing
• sore throat
• unusual tiredness or weakness

Rare side effects

• cloudy or bloody urine
• high blood pressure
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• swelling of the face, feet, or lower legs

Other side effects

Some side effects of rabies immune globulin, human may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• dizziness
• joint pain
• muscle pain
• pain, soreness, tenderness, or stiffness at the injection site

Less common side effects

• fever

Rare side effects

• skin rash

For healthcare professionals

Applies to rabies immune globulin, human: intramuscular solution.

General adverse events

The most common adverse events were injection site and skin reactions.^[Ref]

Local

• Rare (less than 0.1%): Injection site: swelling, pain, erythema, induration, warmth, pruritus, rash
• Frequency not reported: Discomfort at injection site, soreness at injection site^[Ref]

Dermatologic

• Rare (less than 0.1%): Skin reaction, erythema, pruritus, skin rash
• Frequency not reported: Angioneurotic edema, bruising^[Ref]

Hypersensitivity

• Rare (less than 0.1%): Hypersensitivity, anaphylactic shock, allergic type reactions^[Ref]

Other

• Rare (less than 0.1%): Fever, malaise, chill, fatigue, influenza like illness
• Frequency not reported: Mild temperature elevations, disabling pain that limited motion^[Ref]

Renal

• Rare (less than 0.1%): Nephrotic syndrome^[Ref]

Cardiovascular

• Rare (less than 0.1%): Tachycardia, hypotension^[Ref]

Musculoskeletal

• Rare (less than 0.1%): Arthralgia
• Frequency not reported: Compartment syndrome, infiltration of wounds^[Ref]

Gastrointestinal

• Rare (less than 0.1%): Nausea, vomiting^[Ref]

Nervous system

• Rare (less than 0.1%): Headache^[Ref]

Immunologic

• Frequency not reported: Sensitization to repeated injections^[Ref]

Further information

Rabies immune globulin, human side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer