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Pramoxine / zinc oxide topical Side Effects

For the Consumer

Applies to pramoxine / zinc oxide topical: rectal cream

No COMMON side effects have been reported with pramoxine/zinc oxide cream. Seek medical attention right away if any of these SEVERE side effects occur while taking pramoxine / zinc oxide topical:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bleeding from the rectum; new or worsening irritation, pain, redness, swelling, or other symptoms.

For Healthcare Professionals

Applies to pramoxine / zinc oxide topical: topical cream, topical ointment


In general, side effects associated with pramoxine-zinc oxide topical have been reported rarely.[Ref]


1. "Product Information. Tucks Hemorrhoidal (pramoxine-zinc oxide topical)." Pfizer U.S. Pharmaceuticals Group, New York, NY.

It is possible that some side effects of pramoxine / zinc oxide topical may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.