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Pramoxine and zinc oxide topical

Generic Name: pramoxine and zinc oxide topical (pra MOX een and ZINK OX ide TOP ik al)
Brand Name: Tronolane Anesthetic for Hemorrhoids, Tucks Hemorrhoidal, Anusol (obsolete)

Medically reviewed by Drugs.com on Oct 29, 2018 – Written by Cerner Multum

What is pramoxine and zinc oxide topical?

Pramoxine is an anesthetic, or "numbing medicine." It works by interfering with pain signals sent from the nerves to the brain.

Zinc oxide is a mineral.

The combination of pramoxine and zinc oxide topical (for the skin) is used to treat itching, burning, irritation, or other rectal discomfort caused by hemorrhoids or painful bowel movements.

Pramoxine and zinc oxide topical may also be used for purposes not listed in this medication guide.

Important Information

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use this medication if you are allergic to pramoxine, zinc, dimethicone, lanolin, cod liver oil, petroleum jelly, parabens, mineral oil, or wax.

Ask a doctor or pharmacist if it is safe for you to use pramoxine and zinc oxide topical if you are allergic to any drugs or any other numbing medicines.

FDA pregnancy category C. It is not known whether pramoxine and zinc oxide topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether pramoxine and zinc oxide topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I use pramoxine and zinc oxide topical?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Wash your hands before and after applying this medicine. Wash the affected skin area with warm water and a mild soap. Rinse and dry the area thoroughly.

Pramoxine and zinc oxide topical may be used on the rectum after each bowel movement to treat hemorrhoid pain and itching.

Do not insert this medication into your rectum. Use pramoxine and zinc oxide topical only on the outside of the area.

Pramoxine and zinc oxide topical will not treat a bacterial or fungal infection. Call your doctor if you have any signs of infection such as redness and warmth or oozing lesions around your rectum.

Stop using this medicine and call your doctor if your symptoms do not improve after 7 day of treatment, or if your condition clears up and then comes back.

Store at room temperature away from moisture and heat. Keep the cap tightly closed when not in use.

What happens if I miss a dose?

Since pramoxine and zinc oxide topical is used on an as needed basis, you are not likely to miss a dose. Using extra cream or ointment to make up a missed dose will not make the medication more effective.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking pramoxine and zinc oxide topical?

Avoid getting pramoxine and zinc oxide topical in your eyes, nose, or vagina. If this does happen, rinse with water.

Pramoxine and zinc oxide topical side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using pramoxine and zinc oxide topical and call your doctor at once if you have:

  • any new redness or swelling where the medicine was applied;

  • severe pain, burning, or stinging where the medicine is applied; or

  • rectal bleeding or continued pain.

Less serious side effects are more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Pramoxine and zinc oxide topical dosing information

Usual Adult Dose for Hemorrhoids:

Apply externally to the affected area up to 5 times daily. When practical, clean the affected area with mild soap and warm water and rinsing thoroughly. Gently dry by patting with toilet tissue or a soft cloth before applying.

Dispensing Cap:
Attach it to tube, lubricate well, then gently insert part way into anus. Squeeze the tube to deliver medication, then thoroughly cleanse the dispensing cap after use.

Usual Pediatric Dose for Hemorrhoids:

>=12 years:
Apply externally to the affected area up to 5 times daily. When practical, clean the affected area with mild soap and warm water and rinsing thoroughly. Gently dry by patting with toilet tissue or a soft cloth before applying.

Dispensing Cap:
Attach it to tube, lubricate well, then gently insert part way into anus. Squeeze the tube to deliver medication, then thoroughly cleanse the dispensing cap after use.

What other drugs will affect pramoxine and zinc oxide topical?

It is not likely that other drugs you take orally or inject will have an effect on topically applied pramoxine and zinc oxide. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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