Pozelimab Side Effects
Medically reviewed by Drugs.com. Last updated on Nov 10, 2024.
Applies to pozelimab: parenteral injection for iv or sub-q use.
Important warnings
This medicine can cause some serious health issues
-
Serious Meningococcal Infections
- Life-threatening and fatal meningococcal infections reported in patients treated with complement inhibitors; such infections can become rapidly life-threatening or fatal if not recognized and treated early.1
- Complete or update meningococcal vaccinations ≥2 weeks prior to administering first dose of pozelimab-bbfg, unless risks of delaying therapy outweigh those of developing meningococcal infection.1 Follow the most current Advisory Committee on Immunization Practices (ACIP) recommendations for meningococcal vaccination in patients receiving a complement inhibitor.1
- Patients receiving pozelimab-bbfg at increased risk for invasive disease due to Neisseria meningitidis, even if they develop antibodies following vaccination.1
- Monitor patients for early signs of meningococcal infections; evaluate immediately if infection suspected.1
Side effects include:
Adverse effects reported in ≥2 patients include upper respiratory tract infection, fracture, urticaria, alopecia.
For healthcare professionals
Applies to pozelimab: injectable solution.
General adverse events
Most common adverse reactions were upper respiratory tract infection, fracture, urticaria, and alopecia.[Ref]
Cardiovascular
- Frequency not reported: Elevated systolic blood pressure, elevated diastolic blood pressure[Ref]
Dermatologic
- Very common (10% or more): Urticaria (20%), alopecia (20%)[Ref]
Gastrointestinal
- Frequency not reported: Gingival bleeding[Ref]
Hypersensitivity
- Frequency not reported: Systemic hypersensitivity reactions, immune complex formation[Ref]
Local
- Frequency not reported: Injection site reactions (included dermatitis and erythema)[Ref]
Metabolic
- Frequency not reported: Metabolic acidosis, increased blood uric acid[Ref]
Musculoskeletal
- Very common (10% or more): Fracture (30%)[Ref]
Nervous system
- Frequency not reported: Serious meningococcal infections[Ref]
Other
- Frequency not reported: Bacterial infections[Ref]
Respiratory
- Very common (10% or more): Upper respiratory tract infection (30%)[Ref]
Genitourinary
Hepatic
- Frequency not reported: Increased liver enzymes[Ref]
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References
1. (2023) "Product Information. Veopoz (pozelimab)." Regeneron Pharmaceuticals Inc
More about pozelimab
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Further information
Pozelimab side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.
