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Polytrim Side Effects

Generic name: polymyxin b/trimethoprim ophthalmic

Medically reviewed by Drugs.com. Last updated on Mar 13, 2025.

Note: This document provides detailed information about Polytrim Side Effects associated with polymyxin b/trimethoprim ophthalmic. Some dosage forms listed on this page may not apply specifically to the brand name Polytrim.

Applies to polymyxin b/trimethoprim ophthalmic: ophthalmic solution.

Serious side effects of Polytrim

Along with its needed effects, polymyxin b/trimethoprim ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking polymyxin b/trimethoprim ophthalmic:

More common side effects

  • increased redness, burning, stinging, or itching of the eye

Incidence not known

  • blurred vision
  • change in color vision
  • difficulty seeing at night
  • increased sensitivity of the eyes to sunlight
  • increased tearing
  • rash around the eye
  • swelling of the eyelid

Managing side effects (general information)

For healthcare professionals

Applies to polymyxin b/trimethoprim ophthalmic: ophthalmic solution.

Ocular adverse events

Ocular side effects are the most common, and include local irritation, increased redness, burning, stinging, and/or itching. This may occur on instillation, within 48 hours, or at any time with extended use.[Ref]

Hypersensitivity

Hypersensitivity reactions have included lid edema, itching, increased redness, tearing, and/or circumocular rash.[Ref]

Dermatologic

Dermatologic side effects associated with oral trimethoprim have included photosensitivity.[Ref]

References

1. (2022) "Product Information. Polytrim (polymyxin B-trimethoprim ophthalmic)." Allergan Inc

Further information

Polytrim side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer