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Pancuronium Side Effects

For the Consumer

Applies to pancuronium: parenteral injection

Side effects include:

Various degrees of skeletal muscle weakness.

For Healthcare Professionals

Applies to pancuronium: intravenous solution

Hypersensitivity

Uncommon (0.1% to 1%): Severe anaphylactic reactions[Ref]

Local

Uncommon (0.1% to 1%): Pain and burning at injection site[Ref]

Musculoskeletal

Frequency not reported: Prolonged paralysis, disuse atrophy, and areflexia have been reported with prolonged use of this drug[Ref]

Ocular

Frequency not reported: Decreased intraocular pressure, miosis[Ref]

Respiratory

Rare (less than 0.1%): Bronchospasm, wheezing
Frequency not reported: Apnea, respiratory depression[Ref]

Cardiovascular

Very common (10% or more): Mild to moderate increase in blood pressure and/or pulse rate (10%)
Rare (less than 0.1%): Hypotension, cardiovascular collapse, flushing, edema, arrhythmia, bradycardia
Frequency not reported: Dysrhythmias, increased cardiac output[Ref]

Dermatologic

Uncommon (0.1% to 1%): Transient rash, pruritus, redness[Ref]

Gastrointestinal

Frequency not reported: Hypersalivation[Ref]

References

1. "Product Information. Pancuronium Bromide (pancuronium)." Hospira Inc, Lake Forest, IL.

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Some side effects of pancuronium may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

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