Ocufen Side Effects

Generic name: flurbiprofen ophthalmic

Medically reviewed by Drugs.com. Last updated on Apr 4, 2025.

Note: This document provides detailed information about Ocufen Side Effects associated with flurbiprofen ophthalmic. Some dosage forms listed on this page may not apply specifically to the brand name Ocufen.

Applies to flurbiprofen ophthalmic: ophthalmic solution.

Precautions

Your eye doctor will check you closely while you are using this medicine. This is to make sure that the medicine is working properly and not causing unwanted effects.

Slow or delayed healing may occur while you are using this medicine. Ask your doctor before using this medicine together with a steroid eye medicine (e.g., dexamethasone, prednisolone, Ciprodex®).

If you hurt your eye or develop an eye infection, talk with your doctor right away. You may need to change your medicine or stop using it.

While applying this medicine, your eyes will probably sting or burn for a short time. This is to be expected.

Do not use other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of Ocufen

Along with its needed effects, flurbiprofen ophthalmic (the active ingredient contained in Ocufen) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking flurbiprofen ophthalmic:

Other side effects of Ocufen

Some side effects of flurbiprofen ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

See also:

For healthcare professionals

Applies to flurbiprofen ophthalmic: ophthalmic solution.

General adverse events

The most commonly reported side effects were eye irritation, eye pain, and hyphema.^[Ref]

Ocular

• Very common (10% or more): Eye irritation, eye pain, hyphema
• Frequency not reported: Transient burning/stinging upon instillation, fibrosis, miosis, increased bleeding tendency of ocular tissues in conjunction with ocular surgery
• Postmarketing reports: Eye hemorrhage, mydriasis (prolonged mydriasis), ocular hyperemia^[Ref]

Hypersensitivity

• Frequency not reported: Allergic reactions^[Ref]

Further information

Ocufen side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer