Menotropins Side Effects
Commonly reported side effects of menotropins include: ovarian hyperstimulation syndrome, abdominal pain, headache, injection site reaction, and nausea. Other side effects include: respiratory tract disease, abdominal cramps, increased cough, vomiting, epigastric fullness, pain at injection site, and postoperative pain. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to menotropins: injection solution reconstituted, subcutaneous solution reconstituted
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Breast pain.
- Enlarged breasts.
- A fast heartbeat.
- Yellow skin or eyes.
- Fast breathing.
- Pale skin.
- Change in color of skin to a bluish color like on the lips, nail beds, fingers, or toes.
- Flu-like signs.
- Ovarian hyperstimulation syndrome (OHSS) is a very bad side effect that may happen in some women who use this drug. Call your doctor right away if you have very bad stomach pain or bloating; very upset stomach, throwing up, or loose stools (diarrhea); a big weight gain; shortness of breath; or change in how much urine is passed.
- Blood clots have happened with this drug. Sometimes, these blood clots have been deadly. Call your doctor right away if you have chest, arm, back, neck, or jaw pain or pressure; coughing up blood; numbness or weakness on 1 side of your body, trouble speaking or thinking, change in balance, or change in eyesight; shortness of breath; or swelling, warmth, or pain in the leg or arm.
What are some other side effects of this drug?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Irritation where the shot is given.
- Upset stomach.
- Belly pain.
- Stomach cramps.
- Feeling full.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
For Healthcare Professionals
Applies to menotropins: injectable powder for injection, intramuscular powder for injection, subcutaneous powder for injection
The most frequently reported adverse drug reactions reported are abdominal pain, headache, injection site reactions, and injection site pain[Ref]
Very common (10% or more): Multiple pregnancy (35.3%)
Common (1% to 10%): Ovarian Hyperstimulation Syndrome (OHSS), abnormal ovarian enlargement, ovarian disease, vaginal hemorrhage, pelvic pain, breast pain, ectopic pregnancy
Postmarketing reports: Ovarian cyst, breast complaints (including breast tenderness, breast discomfort and breast swelling)
Frequency not reported: Ovarian torsion[Ref]
Common (1% to 10%): Abdominal pain, abdominal cramps, enlarged abdomen, nausea and vomiting, diarrhea, fullness and pain
Postmarketing reports: Nausea, abdominal pain lower, abdominal distension, abdominal discomfort
Frequency not reported: Diarrhea[Ref]
Common (1% to 10%): Infection
Frequency not reported: Formation of antibodies[Ref]
Common (1% to 10%): Injection site pain/reaction, injection site inflammation, injection site edema[Ref]
Common (1% to 10%): Headache
Postmarketing reports: Dizziness[Ref]
Common (1% to 10%): Dyspnea[Ref]
Uncommon (0.1% to 1%): Thrombophlebitis, deep vein thrombosis
Postmarketing reports: Hot flush[Ref]
Frequency not reported: Hypersensitivity[Ref]
Postmarketing reports: Acne, rash, pruritus[Ref]
Postmarketing reports: Arthralgia[Ref]
Postmarketing reports: Visual disorders (blurred vision, vision impairment including amaurosis, diplopia, mydriasis, photopsia, scotoma and vitreous floaters)[Ref]
Postmarketing reports: Fatigue, pyrexia[Ref]
1. "Product Information. Repronex (menotropins)." Ferring Pharmaceuticals Inc, Tarrytown, NY.
2. "Product Information. Menopur (menotropins)." Ferring Pharmaceuticals Inc, Tarrytown, NY.
3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
4. Cerner Multum, Inc. "Australian Product Information." O 0
Some side effects of menotropins may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
More about menotropins
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- En Español
- 1 Review – Add your own review/rating
- Drug class: gonadotropins
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