Magaldrate / simethicone Side Effects

For the Consumer

Applies to magaldrate / simethicone: suspension

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; intestinal pain.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; loss of appetite; muscle weakness; nausea; slow reflexes; vomiting; vomit that looks like coffee grounds.

For Healthcare Professionals

Applies to magaldrate / simethicone: oral suspension, oral tablet chewable

Musculoskeletal

Musculoskeletal side effects including osteomalacia, bone pain, and muscular weakness have been reported with the use of magaldrate.^[Ref]

Other

Other side effects have been reported with the use of magaldrate including malaise, decreased fluoride absorption, milk-alkali syndrome, and aluminum accumulation in serum, bone and the CNS.^[Ref]

Nervous system

Nervous system side effects including neurotoxicity and encephalopathy have been reported with the use of magaldrate.^[Ref]

Gastrointestinal

Gastrointestinal side effects including rebound hyperacidity, diarrhea, intestinal obstruction, and constipation have been reported with the use of magaldrate.^[Ref]

General

Simethicone has no known side effects.^[Ref]

Not all side effects for magaldrate / simethicone may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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