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Lymphoseek Side Effects

Generic name: tilmanocept

Medically reviewed by Last updated on Aug 10, 2022.

Note: This document contains side effect information about tilmanocept. Some dosage forms listed on this page may not apply to the brand name Lymphoseek.

Applies to tilmanocept: injection powder for solution.

Serious side effects of Lymphoseek

Along with its needed effects, tilmanocept (the active ingredient contained in Lymphoseek) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking tilmanocept:

Incidence not known

  • Chest tightness
  • difficulty with breathing or swallowing
  • fast heartbeat
  • fever
  • hives, itching, skin rash
  • hoarseness
  • irritation
  • joint pain, stiffness, or swelling
  • redness of the skin
  • swelling of the eyelids, face, lips, hands, or feet

Other side effects of Lymphoseek

Some side effects of tilmanocept may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


  • Pain or irritation at the injection site

For Healthcare Professionals

Applies to tilmanocept: injectable powder for injection.


Uncommon (0.1% to 1%): Injection site irritation[Ref]


Uncommon (0.1% to 1%): Pain[Ref]


1. "Product Information. Lymphoseek (tilmanocept)." Navidea Biopharmaceuticals (2013):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.