Skip to main content

Lovotibeglogene Autotemcel Side Effects

Applies to lovotibeglogene autotemcel: intravenous suspension.

Important warnings This medicine can cause some serious health issues

Tell your doctor if you use other medicines or have other medical conditions or allergies.

Using lovotibeglogene autotemcel may increase your risk of developing blood cancer. Ask your doctor about your individual risk.

You may get infections or bleed more easily.

Call your doctor if you have severe headache, unusual bleeding or signs of infection (fever, cough, skin sores, painful urination).

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Tell your medical caregivers right away if you have:

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to lovotibeglogene autotemcel: intravenous suspension.

General adverse events

The most commonly reported grade 3 or greater adverse reactions were anemia, febrile neutropenia, leukopenia, neutropenia, stomatitis, and thrombocytopenia.[Ref]

Gastrointestinal

Hematologic

Mobilization and apheresis triggered serious adverse effects of sickle cell crisis in 14% of patients. Sickle cell anemia with crisis included events prior to Month 6 and non-adjudicated occurrences.

Hypersensitivity

Metabolic

Oncologic

Other

Infusion-related reaction events included hot flush and decreased diastolic blood pressure.

Respiratory

Hepatic

References

1. (2023) "Product Information. Lyfgenia (lovotibeglogene autotemcel)." bluebird bio

Further information

Lovotibeglogene autotemcel side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.