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Imogam Rabies-HT Side Effects

Generic name: rabies immune globulin, human

Medically reviewed by Last updated on Jun 5, 2023.

Note: This document contains side effect information about rabies immune globulin, human. Some dosage forms listed on this page may not apply to the brand name Imogam Rabies-HT.

Applies to rabies immune globulin, human: intramuscular solution.

Serious side effects of Imogam Rabies-HT

Along with its needed effects, rabies immune globulin, human (the active ingredient contained in Imogam Rabies-HT) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking rabies immune globulin, human:

More common


Other side effects of Imogam Rabies-HT

Some side effects of rabies immune globulin, human may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common


For Healthcare Professionals

Applies to rabies immune globulin, human: intramuscular solution.


The most common adverse events were injection site and skin reactions.[Ref]


Rare (less than 0.1%): Injection site: swelling, pain, erythema, induration, warmth, pruritus, rash

Frequency not reported: Discomfort at injection site, soreness at injection site[Ref]


Rare (less than 0.1%): Skin reaction, erythema, pruritus, skin rash

Frequency not reported: Angioneurotic edema, bruising[Ref]


Rare (less than 0.1%): Hypersensitivity, anaphylactic shock, allergic type reactions[Ref]


Rare (less than 0.1%): Fever, malaise, chill, fatigue, influenza like illness

Frequency not reported: Mild temperature elevations, disabling pain that limited motion[Ref]


Rare (less than 0.1%): Nephrotic syndrome[Ref]


Rare (less than 0.1%): Tachycardia, hypotension[Ref]


Rare (less than 0.1%): Arthralgia

Frequency not reported: Compartment syndrome, infiltration of wounds[Ref]


Rare (less than 0.1%): Nausea, vomiting[Ref]

Nervous system

Rare (less than 0.1%): Headache[Ref]


Frequency not reported: Sensitization to repeated injections[Ref]


1. Cerner Multum, Inc. UK Summary of Product Characteristics.

2. Product Information. Imogam Rabies-HT (rabies immune globulin, human). sanofi pasteur. 2010.

3. Product Information. Hyperrab S/D (rabies immune globulin, human). Grifols Therapeutics. 2015.

4. Cerner Multum, Inc. Australian Product Information.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.