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HMS Side Effects

Generic name: medrysone ophthalmic

Note: This document contains side effect information about medrysone ophthalmic. Some dosage forms listed on this page may not apply to the brand name HMS.

Applies to medrysone ophthalmic: ophthalmic suspension.


Do not stop using this medication suddenly if you have been using it for several weeks or more. Before stopping, you may need to reduce the dose over several days to prevent side effects.

Contact your doctor if your symptoms begin to get worse or if you do not see any improvement in your condition after a few days.

Do not touch the dropper to any surface, including your eyes or hands. The dropper is sterile. If it becomes contaminated, it could cause an infection in your eye.

Apply light pressure to the inside corner of your eye (near your nose) after each drop to prevent the fluid from draining down your tear ducts.

Serious side effects are not expected with this medication. Rarely, an increase in the pressure inside of the eye, formation of cataracts, or perforation of the cornea have been reported. Talk to your doctor about any possible side effects.

More commonly, some burning, stinging, irritation, itching, redness, blurred vision or sensitivity to light may occur. Continue to use medrysone ophthalmic (the active ingredient contained in HMS) and talk to your doctor about any side effects that you experience.

For Healthcare Professionals

Applies to medrysone ophthalmic: ophthalmic suspension.


Ocular side effects have included burning and stinging upon instillation. Less frequent ocular side effects include elevation of intraocular pressure with possible development of glaucoma, visual field defects, posterior subcapsular cataract formation, and optic nerve damage.

Corticosteroid containing preparations have also been reported to cause acute anterior uveitis, perforation of the globe, keratitis, conjunctivitis, corneal ulcers, mydriasis, conjunctival hyperemia, loss of accommodation, and ptosis.[Ref]


1. (2001) "Product Information. HMS (medrysone ophthalmic)." Allergan Inc

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.