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Glucagon Side Effects

For the Consumer

Applies to glucagon: injection powder for solution

Along with its needed effects, glucagon may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking glucagon:


Incidence Not Known

  • Difficulty with swallowing
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast, pounding, or irregular heartbeat or pulse
  • hives, itching, or skin rash
  • pounding in the ears
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • slow or fast heartbeat
  • sweating
  • tightness in the chest

Some side effects of glucagon may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less Common

For Healthcare Professionals

Applies to glucagon: injectable powder for injection


The more commonly reported adverse reactions have included nausea and vomiting.[Ref]


Hypoglycemia/hypoglycemia coma have been reported in patients using this drug as a diagnostic aid, especially among those patients who have fasted.

Uncommon (0.1% to 1%): Hypoglycemia

Very rare (less than 0.01%): Hypoglycemia coma


Common (1% to 10%): Nausea

Uncommon (0.1% to 1%): Vomiting

Rare (less than 0.1%): Abdominal pain[Ref]


Very rare (less than 0.01%): Anaphylactic reactions

Frequency not reported: Generalized allergic reactions[Ref]


Postmarketing reports: Necrolytic migratory erythema (with continuous glucagon infusions)


Very rare (less than 0.01%): Bradycardia, tachycardia, hypotension, hypertension


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. "Product Information. GlucaGen (glucagon)." Novo Nordisk Pharmaceuticals Inc, Princeton, NJ.

3. Cerner Multum, Inc. "Australian Product Information." O 0

4. "Product Information. Glucagon (glucagon)." Lilly, Eli and Company, Indianapolis, IN.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.