Galafold Side Effects

Generic name: migalastat

Medically reviewed by Drugs.com. Last updated on Jan 22, 2024.

Note: This document provides detailed information about Galafold Side Effects associated with migalastat. Some dosage forms listed on this page may not apply specifically to the brand name Galafold.

Applies to migalastat: oral capsule.

Serious side effects of Galafold

Along with its needed effects, migalastat (the active ingredient contained in Galafold) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking migalastat:

More common side effects

• bladder pain
• bloody or cloudy urine
• difficult, burning, or painful urination
• frequent urge to urinate
• lower back or side pain

Other side effects of Galafold

Some side effects of migalastat may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• back pain
• cough
• diarrhea
• fever
• headache
• muscle aches
• nausea
• nosebleed
• sore throat
• stomach pain
• stuffy or runny nose
• unusual tiredness or weakness

For healthcare professionals

Applies to migalastat: oral capsule.

General adverse events

The more commonly reported adverse effects have included headache, nasopharyngitis, urinary tract infection, nausea, and pyrexia.^[Ref]

Nervous system

• Very common (10% or more): Headache (35%)
• Common (1% to 10%): Paresthesia, dizziness, hypoesthesia

Respiratory

• Very common (10% or more): Nasopharyngitis (18%)
• Common (1% to 10%): Cough, epistaxis, dyspnea

Renal

• Common (1% to 10%): Proteinuria

Gastrointestinal

• Very common (10% or more): Nausea (12%)
• Common (1% to 10%): Abdominal pain, diarrhea, vomiting, constipation, dry mouth, defection urgency, dyspepsia

Musculoskeletal

• Common (1% to 10%): Back pain, muscle spasms, myalgia, torticollis, extremity pain, increased blood creatine phosphokinase

Metabolic

• Common (1% to 10%): Increased weight

Genitourinary

• Very common (10% or more): Urinary tract infection (15%)

Urinary tract infection includes cystitis, and kidney infection.

Other

• Common (1% to 10%): Pyrexia, vertigo, fatigue

Psychiatric

• Common (1% to 10%): Depression

Cardiovascular

• Common (1% to 10%): Palpitations

Dermatologic

• Common (1% to 10%): Rash, pruritus

Frequently asked questions

• What is an amenable mutation?
• How much does Galafold cost?

Further information

Galafold side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer