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Florexa Side Effects

Generic name: eflornithine topical

Medically reviewed by Drugs.com. Last updated on Dec 23, 2022.

Note: This document contains side effect information about eflornithine topical. Some dosage forms listed on this page may not apply to the brand name Florexa.

Applies to eflornithine topical: topical cream.

Other side effects of Florexa

Some side effects of eflornithine topical (the active ingredient contained in Florexa) may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Acne
  • stinging skin

Less common

  • Burning or bleeding skin
  • chapped, red lips
  • chronic acne
  • hair bumps
  • numbness
  • rash
  • reddening of skin
  • swelling of lips
  • tingling skin

For Healthcare Professionals

Applies to eflornithine topical: topical cream.

General

The most frequently reported side effects were dermatologic in nature and included acne and pseudofolliculitis barbae.[Ref]

Dermatologic

Very common (10% or more): Acne (up to 21.3 %), pseudofolliculitis barbae (up to 16.3%)

Common (1% to 10%): Stinging skin, burning skin, dry skin, pruritus, erythema, tingling skin, skin irritated, rash, alopecia

Uncommon (0.1% to 1%): Ingrown hair, papular rash, skin bleeding, eczema, contact dermatitis, hair texture abnormal, hair growth abnormal, skin hypopigmentation, skin soreness

Rare (less than 0.1%): Rosacea, seborrheic dermatitis, maculopapular rash, skin cyst, vesiculobullous rash, skin disorder, hirsutism, skin tightness[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness

Frequency not reported: Numbness[Ref]

Gastrointestinal

Common (1% to 10%): Dyspepsia

Uncommon (0.1% to 1%): Nausea, cheilitis, numb lip

Frequency not reported: Swollen lip[Ref]

Cardiovascular

Uncommon (0.1% to 1%): Flushing[Ref]

Other

Common (1% to 10%): Folliculitis

Uncommon (0.1% to 1%): Facial edema, asthenia, vertigo, mouth edema, herpes simplex, furunculosis[Ref]

Metabolic

Uncommon (0.1% to 1%): Anorexia[Ref]

Oncologic

Rare (less than 0.1%): Skin neoplasm[Ref]

More about Florexa (eflornithine topical)

Patient resources

Other brands

Vaniqa

Professional resources

Related treatment guides

References

1. "Product Information. Vaniqa (eflornithine topical)." Bristol-Myers Squibb (2001):

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. Cerner Multum, Inc. "Australian Product Information." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.