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Dexchlorpheniramine / phenylephrine Side Effects

Applies to dexchlorpheniramine / phenylephrine: oral tablet.


Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Do not use this medicine only to make a child sleepy.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to dexchlorpheniramine/phenylephrine: oral tablet, oral tablet extended release.


Gastrointestinal side effects have included nausea, dry mouth, anorexia, and heartburn.[Ref]

Nervous system

Nervous system side effects have included headache, dizziness, mild sedation, tremor, weakness, insomnia, drowsiness, restlessness, convulsions, central nervous system depression, and nervousness.[Ref]


Genitourinary side effects have included dysuria.[Ref]


Psychiatric side effects have included fear, anxiety, and tenseness.[Ref]


Cardiovascular side effects have included pallor, tachycardia, palpitations, arrhythmias, and cardiovascular collapse with hypotension.[Ref]


Respiratory side effects have included respiratory difficulty.[Ref]


Dermatologic side effects have included very rare reports of dermatitis.[Ref]


Ocular side effects have included blurring of vision.[Ref]


1. (2007) "Product Information. RhinaHist (dexchlorpheniramine-phenylephrine)." Kowa Pharmaceuticals America (formerly ProEthic)

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.