CytoGam Side Effects
Generic Name: cytomegalovirus immune globulin
Note: This document contains side effect information about cytomegalovirus immune globulin. Some of the dosage forms listed on this page may not apply to the brand name CytoGam.
For the Consumer
Applies to cytomegalovirus immune globulin: parenteral injection for iv infusion
Side effects include:
For Healthcare Professionals
Applies to cytomegalovirus immune globulin: intravenous solution
The most frequent side effects have included minor reactions such as flushing, chills, muscle cramps, back pain, fever, nausea, vomiting, arthralgia, and wheezing in < 6.0% of all infusions. These reactions were most often related to the infusion rate. A decrease in blood pressure was observed in 1 of 1039 infusions in clinical trials. If a minor reaction occurs, the infusion should be slowed or temporarily interrupted.[Ref]
Renal side effects have included increases in serum creatinine and blood urea nitrogen (BUN) within 1 to 2 days after IGIV infusion, oliguria or anuria requiring dialysis, acute renal failure, acute tubular necrosis, proximal tubular nephropathy, and osmotic nephrosis.[Ref]
Hepatic side effects have included hepatic dysfunction.[Ref]
Hypersensitivity reactions including angioneurotic edema and anaphylactic shock may occur. Clinical anaphylaxis may occur even when the patient is not known to be sensitized to immune globulin products. A reaction may be related to the rate of infusion.[Ref]
Musculoskeletal side effects have included back pain.[Ref]
Respiratory side effects have included apnea, acute respiratory distress syndrome (ARDS), transfusion associated lung injury (TRALI), cyanosis, hypoxemia, pulmonary edema, dyspnea, and bronchospasm.[Ref]
Other side effects have included pyrexia and rigors.[Ref]
1. "Product Information. Cytogam (cytomegalovirus immune globulin)." Medimmune Inc, Gaithersburg, MD.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
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- Drug class: immune globulins