CytoGam Side Effects
Generic Name: cytomegalovirus immune globulin
Note: This page contains information about the side effects of cytomegalovirus immune globulin. Some of the dosage forms included on this document may not apply to the brand name CytoGam.
For the Consumer
Applies to cytomegalovirus immune globulin: parenteral injection for iv infusion
Side effects include:
Flushing, chills, muscle cramps, back pain, fever, nausea, vomiting, arthralgia, wheezing/shortness of breath/chest tightness.
For Healthcare Professionals
Applies to cytomegalovirus immune globulin: intravenous solution
The most frequent side effects have included minor reactions such as flushing, chills, muscle cramps, back pain, fever, nausea, vomiting, arthralgia, and wheezing in < 6.0% of all infusions. These reactions were most often related to the infusion rate. A decrease in blood pressure was observed in 1 of 1039 infusions in clinical trials. If a minor reaction occurs, the infusion should be slowed or temporarily interrupted.[Ref]
Renal side effects have included increases in serum creatinine and blood urea nitrogen (BUN) within 1 to 2 days after IGIV infusion, oliguria or anuria requiring dialysis, acute renal failure, acute tubular necrosis, proximal tubular nephropathy, and osmotic nephrosis.[Ref]
Cardiovascular side effects have included cardiac arrest, thromboembolism, vascular collapse, and hypotension.[Ref]
Dermatologic side effects have included Stevens-Johnson syndrome, epidermolysis, erythema multiforme, and bullous dermatitis.[Ref]
Gastrointestinal side effects have included abdominal pain.[Ref]
Hematologic side effects have included pancytopenia, leukopenia, hemolysis, and positive direct antiglobulin (Coombs) test.[Ref]
Hepatic side effects have included hepatic dysfunction.[Ref]
Hypersensitivity reactions including angioneurotic edema and anaphylactic shock may occur. Clinical anaphylaxis may occur even when the patient is not known to be sensitized to immune globulin products. A reaction may be related to the rate of infusion.[Ref]
Musculoskeletal side effects have included back pain.[Ref]
Nervous system side effects have included coma, loss of consciousness, seizures, and tremor.[Ref]
Respiratory side effects have included apnea, acute respiratory distress syndrome (ARDS), transfusion associated lung injury (TRALI), cyanosis, hypoxemia, pulmonary edema, dyspnea, and bronchospasm.[Ref]
Other side effects have included pyrexia and rigors.[Ref]
1. "Product Information. Cytogam (cytomegalovirus immune globulin)." Medimmune Inc, Gaithersburg, MD.
Not all side effects for CytoGam may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
More about CytoGam (cytomegalovirus immune globulin)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 0 Reviews – Add your own review/rating
- Drug class: immune globulins
Related treatment guides
Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.