CytoGam Side Effects

Generic name: cytomegalovirus immune globulin

Medically reviewed by Drugs.com. Last updated on Aug 22, 2024.

Note: This document provides detailed information about CytoGam.

Applies to cytomegalovirus immune globulin: parenteral injection for iv infusion Side Effects associated with cytomegalovirus immune globulin. Some dosage forms listed on this page may not apply specifically to the brand name CytoGam.

Applies to cytomegalovirus immune globulin: parenteral injection for iv infusion.

Side effects include:

Flushing, chills, muscle cramps, back pain, fever, nausea, vomiting, arthralgia, wheezing/shortness of breath/chest tightness.

For healthcare professionals

Applies to cytomegalovirus immune globulin: intravenous solution.

General adverse events

The most common adverse events were flushing, chills, muscle cramps, back pain, fever, nausea, vomiting, arthralgia, and wheezing. Such reactions are most often related to infusion rates.^[Ref]

Renal

• Frequency not reported: Increases in serum creatinine, increase in blood urea nitrogen (BUN), acute renal failure, acute tubular necrosis, proximal tubular nephropathy, osmotic nephrosis^[Ref]

Cardiovascular

• Uncommon (0.1% to 1%): Decrease in blood pressure
• Frequency not reported: Flushing
• Postmarketing reports: Cardiac arrest, thromboembolism, vascular collapse, hypotension^[Ref]

Dermatologic

• Postmarketing reports: Stevens-Johnson syndrome, epidermolysis, erythema multiforme, bullous dermatitis^[Ref]

Gastrointestinal

• Frequency not reported: Nausea, vomiting
• Postmarketing reports: Abdominal pain^[Ref]

Hematologic

• Postmarketing reports: Pancytopenia, leukopenia, hemolysis, positive direct antiglobulin (Coombs) test^[Ref]

Hepatic

• Postmarketing reports: Hepatic dysfunction^[Ref]

Musculoskeletal

• Frequency not reported: Chills, muscle cramps, back pain, arthralgia^[Ref]

Nervous system

• Postmarketing reports: Coma, loss of consciousness, seizures, tremor^[Ref]

Respiratory

• Frequency not reported: Wheezing
• Postmarketing reports: Apnea, acute respiratory distress syndrome (ARDS), transfusion related acute lung injury (TRALI), cyanosis, hypoxemia, pulmonary edema, dyspnea, bronchospasm^[Ref]

Other

• Postmarketing reports: Fever, rigors^[Ref]

Genitourinary

• Frequency not reported: Oliguria, anuria requiring dialysis

Further information

CytoGam side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer