Skip to main content

CytoGam Side Effects

Generic name: cytomegalovirus immune globulin

Medically reviewed by Last updated on Aug 22, 2023.

Note: This document contains side effect information about cytomegalovirus immune globulin. Some dosage forms listed on this page may not apply to the brand name CytoGam.

Applies to cytomegalovirus immune globulin: parenteral injection for iv infusion.

Side effects include:

Flushing, chills, muscle cramps, back pain, fever, nausea, vomiting, arthralgia, wheezing/shortness of breath/chest tightness.

For Healthcare Professionals

Applies to cytomegalovirus immune globulin: intravenous solution.


The most common adverse events were flushing, chills, muscle cramps, back pain, fever, nausea, vomiting, arthralgia, and wheezing. Such reactions are most often related to infusion rates.[Ref]


Frequency not reported: Increases in serum creatinine, increase in blood urea nitrogen (BUN), acute renal failure, acute tubular necrosis, proximal tubular nephropathy, osmotic nephrosis[Ref]


Uncommon (0.1% to 1%): Decrease in blood pressure

Frequency not reported: Flushing

Postmarketing reports: Cardiac arrest, thromboembolism, vascular collapse, hypotension[Ref]


Postmarketing reports: Stevens-Johnson syndrome, epidermolysis, erythema multiforme, bullous dermatitis[Ref]


Frequency not reported: Nausea, vomiting

Postmarketing reports: Abdominal pain[Ref]


Postmarketing reports: Pancytopenia, leukopenia, hemolysis, positive direct antiglobulin (Coombs) test[Ref]


Postmarketing reports: Hepatic dysfunction[Ref]


Frequency not reported: Chills, muscle cramps, back pain, arthralgia[Ref]

Nervous system

Postmarketing reports: Coma, loss of consciousness, seizures, tremor[Ref]


Frequency not reported: Wheezing

Postmarketing reports: Apnea, acute respiratory distress syndrome (ARDS), transfusion related acute lung injury (TRALI), cyanosis, hypoxemia, pulmonary edema, dyspnea, bronchospasm[Ref]


Postmarketing reports: Fever, rigors[Ref]


Frequency not reported: Oliguria, anuria requiring dialysis


1. (2002) "Product Information. Cytogam (cytomegalovirus immune globulin)." CSL Behring LLC

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.