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Codeine / diphenhydramine / phenylephrine Side Effects

Applies to codeine/diphenhydramine/phenylephrine: oral syrup

Nervous system

Nervous system side effects have included drowsiness, dizziness, headache, nervousness, restlessness, impairment of mental performance, weakness, mental clouding, lethargy, anxiety, convulsions, CNS depression, tremor, and insomnia.[Ref]

Psychiatric

Psychiatric side effects have included fear, dysphoria, psychic dependence, feeling of well-being, confusion, and mood changes.[Ref]

Cardiovascular

Cardiovascular side effects have included tachycardia, palpitations, arrhythmias, change in heart rate, and cardiovascular collapse with hypotension.[Ref]

Gastrointestinal

Gastrointestinal side effects have included loss of appetite, nausea, constipation, dry mouth, anorexia, vomiting, and heartburn.[Ref]

Genitourinary

Genitourinary side effects have included dysuria, polyuria, ureteral spasm, spasm of vesical sphincters, urinary disturbances, and urinary retention.[Ref]

Respiratory

Respiratory side effects have included respiratory difficulty and respiratory depression.[Ref]

Dermatologic

Dermatologic side effects have included increased sweating, pallor, skin hash, hives, swelling of face, and dermatitis.[Ref]

Ocular

Ocular side effects have included blurring of vision and visual disturbances.[Ref]

References

1. "Product Information. Endal CD (codeine / diphenhydramine / phenylephrine)." Tiber Laboratories, Suwanee, GA.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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