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Cetraxal Side Effects

Generic name: ciprofloxacin otic

Medically reviewed by Last updated on Jan 21, 2024.

Note: This document contains side effect information about ciprofloxacin otic. Some dosage forms listed on this page may not apply to the brand name Cetraxal.

Applies to ciprofloxacin otic: intratympanic suspension. Other dosage forms:

Serious side effects of Cetraxal

Along with its needed effects, ciprofloxacin otic (the active ingredient contained in Cetraxal) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking ciprofloxacin otic:

Less common

Other side effects of Cetraxal

Some side effects of ciprofloxacin otic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

For Healthcare Professionals

Applies to ciprofloxacin otic: otic solution, otic suspension.


The most commonly reported side effects included application site pain, ear pruritus, and headache.[Ref]


Common (1% to 10%): Ear pruritus, ear pain, ear discomfort/stinging, otitis media, ear infection (fungal; otomycosis)/fungal ear superinfection

Postmarketing reports: Crying, ear congestion, otorrhea, pyrexia[Ref]

Nervous system

Common (1% to 10%): Headache/cephalea, dizziness, vertigo, dysgeusia/bitter taste

Uncommon (0.1% to 1%): Tinnitus[Ref]


Common (1% to 10%): Irritability[Ref]


Common (1% to 10%): Nasopharyngitis, rhinorrhea[Ref]


Common (1% to 10%): Mild local intolerance, application site pain[Ref]


Uncommon (0.1% to 1%): Dermatitis

Locally-applied fluoroquinolones:

-Very rare (less than 0.01%): Toxic epidermolysis, exfoliative dermatitis, generalized rash, Stevens-Johnson syndrome, urticaria


Frequency not reported: Allergic reaction

Systemic quinolone therapy:

-Frequency not reported: Serious and sometimes fatal hypersensitivity (anaphylactic) reactions (some accompanied by cardiovascular collapse, loss of consciousness, tingling, pharyngeal/facial edema, dyspnea, urticaria, itching)


Systemic fluoroquinolones:

-Frequency not reported: Tendon rupture (e.g., shoulder, hand, Achilles)


1. Cerner Multum, Inc. UK Summary of Product Characteristics.

2. Cerner Multum, Inc. Australian Product Information.

3. Product Information. Cetraxal (ciprofloxacin otic). WraSer Pharmaceuticals. 2009.

4. Product Information. Otiprio (ciprofloxacin otic). Otonomy, Inc. 2015.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.