Carbinoxamine / Dextromethorphan / Phenylephrine Side Effects

Applies to carbinoxamine/dextromethorphan/phenylephrine: oral liquid.

Important warnings This medicine can cause some serious health issues

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Do not use any other over-the-counter cough or cold medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant.

Do not use carbinoxamine, dextromethorphan, and phenylephrine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take carbinoxamine, dextromethorphan, and phenylephrine before the MAO inhibitor has cleared from your body.

Carbinoxamine, dextromethorphan, and phenylephrine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of this medication.

Call your doctor if you have a fever, or if your symptoms get worse or do not improve after taking this medicine for 7 days.

Do not take this product for cough caused by smoking, asthma, or emphysema. Do not take this medicine if your cough produces a lot of mucus, unless your doctor has told you to.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

• feeling light-headed, fainting;

• urinating less than usual or not at all;

• wheezing, tightness in your chest;

• fast or pounding heartbeat; or

• pale skin, easy bruising or bleeding.

Keep taking the medication and talk to your doctor if you have any of these less serious side effects:

• drowsiness, dizziness;

• lack of coordination;

• upset stomach;

• stuffy nose, chest congestion;

• sleep problems (insomnia);

• feeling restless or excited (especially in children);

• dry mouth or nose; or

• blurred vision.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

For healthcare professionals

Applies to carbinoxamine / dextromethorphan / phenylephrine: oral liquid.

Cardiovascular

Cardiovascular side effects have included pallor, arrhythmias and increased heart rate or blood pressure.^[Ref]

Nervous system

Nervous system side effects have included sedation, dizziness, headache, nervousness, convulsions, central nervous system stimulation, hallucinations, tremor, insomnia, and weakness.^[Ref]

Ocular

Ocular side effects have included diplopia.^[Ref]

Respiratory

Respiratory side effects have included respiratory difficulty.^[Ref]

Gastrointestinal

Gastrointestinal side effects have included nausea, vomiting, anorexia, heartburn and diarrhea.^[Ref]

Genitourinary

Genitourinary side effects have included dysuria and polyuria.^[Ref]

Further information

Carbinoxamine/dextromethorphan/phenylephrine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer