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Botulism antitoxin Side Effects

Medically reviewed by Last updated on Jul 23, 2022.

Applies to botulism antitoxin: parenteral for injection for iv use.

Side effects include:

Headache, nausea, pruritus, urticaria, fever, rash, chills, edema.

For Healthcare Professionals

Applies to botulism antitoxin: injectable solution.


Uncommon (0.1% to 1%): Serum sickness

Frequency not reported: Hypersensitivity reactions

Postmarketing reports: Anaphylactic shock[Ref]


Common (1% to 10%): Pyrexia, chills, edema

Uncommon (0.1% to 1%): Feeling jittery, chest discomfort

Frequency not reported: Infusion reactions[Ref]


Uncommon (0.1% to 1%): Blood pressure increased

Uncommon (0.1% to 1%): Hemodynamic instability (bradycardia, tachycardia, and asystole during administration), hypotension[Ref]


Uncommon (0.1% to 1%): White blood cell count increased[Ref]


Common (1% to 10%): Pruritus, urticaria, rash

Uncommon (0.1% to 1%): Hyperhidrosis, erythema

Postmarketing reports: Angioedema[Ref]


Common (1% to 10%): Nausea, throat discomfort[Ref]


Uncommon (0.1% to 1%): Agitation, anxiety[Ref]


Uncommon (0.1% to 1%): Bronchospasm[Ref]


Uncommon (0.1% to 1%): Urinary retention[Ref]

Nervous system

Common (1% to 10%): Headache[Ref]

More about botulism antitoxin

Patient resources

Professional resources

Related treatment guides


1. "Product Information. Botulism Antitoxin (botulism antitoxin)." sanofi pasteur (2019):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.