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Bayrab Side Effects

Generic name: rabies immune globulin, human

Medically reviewed by Last updated on Mar 9, 2022.

Note: This document contains side effect information about rabies immune globulin, human. Some of the dosage forms listed on this page may not apply to the brand name Bayrab.

For the Consumer

Applies to rabies immune globulin, human: intramuscular solution

Side effects requiring immediate medical attention

Along with its needed effects, rabies immune globulin, human (the active ingredient contained in Bayrab) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking rabies immune globulin, human:

More common


  • Cloudy or bloody urine
  • high blood pressure
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • swelling of the face, feet, or lower legs

Side effects not requiring immediate medical attention

Some side effects of rabies immune globulin, human may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Dizziness
  • joint pain
  • muscle pain
  • pain, soreness, tenderness, or stiffness at the injection site

Less common

  • Fever


For Healthcare Professionals

Applies to rabies immune globulin, human: intramuscular solution


The most common adverse events were injection site and skin reactions.[Ref]


Rare (less than 0.1%): Injection site: swelling, pain, erythema, induration, warmth, pruritus, rash

Frequency not reported: Discomfort at injection site, soreness at injection site[Ref]


Rare (less than 0.1%): Skin reaction, erythema, pruritus, skin rash

Frequency not reported: Angioneurotic edema, bruising[Ref]


Rare (less than 0.1%): Hypersensitivity, anaphylactic shock, allergic type reactions[Ref]


Rare (less than 0.1%): Fever, malaise, chill, fatigue, influenza like illness

Frequency not reported: Mild temperature elevations, disabling pain that limited motion[Ref]


Rare (less than 0.1%): Nephrotic syndrome[Ref]


Rare (less than 0.1%): Tachycardia, hypotension[Ref]


Rare (less than 0.1%): Arthralgia

Frequency not reported: Compartment syndrome, infiltration of wounds[Ref]


Rare (less than 0.1%): Nausea, vomiting[Ref]

Nervous system

Rare (less than 0.1%): Headache[Ref]


Frequency not reported: Sensitization to repeated injections[Ref]

More about Bayrab (rabies immune globulin, human)

Patient resources

Other brands

HyperRAB S/D, Imogam Rabies-HT, KedRAB

Professional resources

Related treatment guides


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. "Product Information. Imogam Rabies-HT (rabies immune globulin, human)." sanofi pasteur (2010):

3. "Product Information. Hyperrab S/D (rabies immune globulin, human)." Grifols Therapeutics (2015):

4. Cerner Multum, Inc. "Australian Product Information." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.