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Antizol Side Effects

Generic Name: fomepizole

Note: This page contains information about the side effects of fomepizole. Some of the dosage forms included on this document may not apply to the brand name Antizol.

In Summary

Common side effects of Antizol include: headache and nausea. Other side effects include: dizziness. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to fomepizole: intravenous solution

Get emergency medical help if you have any of these signs of an allergic reaction while taking fomepizole (the active ingredient contained in Antizol) hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregiver right away if you have:

  • skin rash, bruising, severe tingling, numbness, pain, muscle weakness.

  • severe nausea, severe dizziness or spinning sensation; or

  • a light-headed feeling, like you might pass out.

Common side effects may include:

  • headache;

  • dizziness, drowsiness;

  • nausea; or

  • unpleasant or metallic taste in your mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to fomepizole: intravenous solution

General

The most common adverse events were headache, nausea, dizziness, increased drowsiness, and bad taste/metallic taste.[Ref]

Gastrointestinal

Very common (10% or more): Nausea (11%)
Common (1% to 10%): Abdominal pain, vomiting, diarrhea, dyspepsia, heartburn[Ref]

Nervous system

Very common (10% or more): Headache (14%)
Common (1% to 10%): Dizziness, increased drowsiness, bad taste/metallic taste, lightheadedness, seizure, agitation, feeling drunk, vertigo, nystagmus, anxiety, "felt strange", decreased environmental awareness, abnormal smell, roar in ear[Ref]

Other

Common (1% to 10%): Fever, multiorgan system failure, hangover, speech/visual disturbances[Ref]

Cardiovascular

Common (1% to 10%): Sinus bradycardia/bradycardia, phlebosclerosis, tachycardia, phlebitis, shock, hypotension[Ref]

Hematologic

Common (1% to 10%): Eosinophilia/hypereosinophilia, lymphangitis, disseminated intravascular coagulation, anemia[Ref]

Hepatic

Common (1% to 10%): Transient transaminitis[Ref]

Local

Common (1% to 10%): Pain during injection, inflammation at injection site, application site reaction[Ref]

Genitourinary

Common (1% to 10%): Anuria[Ref]

Respiratory

Common (1% to 10%): Hiccups, pharyngitis[Ref]

Ocular

Common (1% to 10%): Transient blurred vision[Ref]

Dermatologic

Common (1% to 10%): Facial flush, rash[Ref]

Musculoskeletal

Common (1% to 10%): Lumbalgia/backache[Ref]

Metabolic

Common (1% to 10%): Decreased appetite

References

1. "Product Information. Antizol (fomepizole)." Jazz Pharmaceuticals, Palo Alto, CA.

Not all side effects for Antizol may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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