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Generic name: anti-inhibitor coagulant complexan-TEE-in-HIB-i-tor-koe-AG-yoo-lant-KOM-plex ]
Brand names: Feiba, Feiba VH Immuno

Medically reviewed by on Feb 27, 2023. Written by Cerner Multum.

What is Feiba?

Feiba is used in people who have hemophilia and have developed antibodies to clotting factor medications.

Hemophilia, an inherited blood-clotting disorder, is often treated with medicines containing clotting factors that help control bleeding. When the body develops antibodies or "inhibitors" to the clotting factor, this treatment becomes less effective in preventing bleeding episodes. Feiba works by bypassing the effects of these inhibitors to improve blood clotting and decrease the risk of bleeding.

Feiba is used to treat or prevent bleeding episodes in people with hemophilia A or B who have developed inhibitors. Feiba is also used to control bleeding related to surgery in people with hemophilia and inhibitors. This medicine is not for treating bleeding episodes in people who do not have inhibitors.

Feiba may also be used for purposes not listed in this medication guide.

Feiba side effects

Get emergency medical help if you have signs of an allergic reaction: hives; wheezing, difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor or seek emergency medical help right away if you have:

Common side effects of Feiba may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Feiba may increase your risk of having a stroke or heart attack.

Call your doctor or seek emergency medical help right away if you have--sudden numbness or weakness, sudden headache, slurred speech, chest pain, trouble breathing, sudden cough with blood, warmth or swelling in your leg.

Before taking this medicine

You should not use Feiba if:

To make sure Feiba is safe for you, tell your doctor if you have:

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether anti-inhibitor coagulant complex passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Feiba is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.

How should I use Feiba?

Feiba is injected into a vein through an IV. You may be shown how to use an IV at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of needles, IV tubing, and other items used.

To treat a bleeding episode, this medicine is usually given once every 6 to 12 hours until your condition improves. For routine prevention of bleeding, Feiba may be given every other day. Follow your doctor's dosing instructions very carefully.

If a child is using this medicine, tell your doctor if the child has any changes in weight. Feiba doses are based on weight in children, and any changes may affect your child's dose.

Feiba is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine.

Do not use the medicine if it has changed colors or has particles in it. Call your pharmacist for new medicine.

Use a disposable needle and syringe only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.

Each single-use vial (bottle) of this medicine is for one use only. Throw away after one use, even if there is still some medicine left in it after injecting your dose.

Keep the medicine and diluent in their original container and store at room temperature, away from moisture, heat, and light. Do not allow the medicine to freeze.

After mixing Feiba with the diluent, store the mixture at room temperature and use it within 3 hours. Do not refrigerate mixed medicine.

Wear a medical alert tag or carry an ID card stating that you have hemophilia. Any doctor, dentist, or emergency medical care provider who treats you should know that you have a bleeding or blood-clotting disorder.

What happens if I miss a dose?

Call your doctor for instructions if you miss a dose of Feiba.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Feiba?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect Feiba?

Tell your doctor about all your current medicines and any you start or stop using, especially:

This list is not complete. Other drugs may interact with anti-inhibitor coagulant complex, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

More about Feiba (anti-inhibitor coagulant complex)

Patient resources

Other brands

Autoplex T, Feiba NF, Feiba VH

Professional resources

Other brands

Feiba NF

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.