Coagulation factor VIIa (injection)
Generic name: coagulation factor VIIa (injection) [ koe-AG-yoo-LAY-shun-FAK-tor ]
Brand names: NovoSeven RT with MixPro, SevenFACT, NovoSeven, NovoSeven RT
Dosage forms: intravenous injection (jncw 1000 mcg (1 mg), jncw 5000 mcg (5 mg)), intravenous powder for injection (1000 mcg (1 mg),
... show all 6 dosage forms
Drug class: Miscellaneous coagulation modifiers
What is coagulation factor VIIa?
Coagulation factor VIIa is a man-made protein similar to a natural protein in the body that helps the blood to clot.
Coagulation factor VIIa is used to treat or prevent bleeding in people with hemophilia A or hemophilia B, or factor VII deficiency.
Coagulation factor VIIa may also be used for purposes not listed in this medication guide.
Coagulation factor VIIa side effects
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Coagulation factor VIIa may cause serious side effects. Call your doctor at once if you have:
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signs of a stroke--sudden numbness or weakness (especially on one side of the body), severe headache, slurred speech, problems with vision or balance;
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signs of a blood clot in the lung--chest pain, sudden cough or shortness of breath, dizziness, coughing up blood;
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signs of a blood clot deep in the body--pain, swelling, or warmth in one leg;
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fever;
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little or no urination;
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feeling that you might pass out; or
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any bleeding that will not stop.
Common side effects of coagulation factor VIIa may include:
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mild headache;
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nausea, vomiting;
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swelling;
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mild itching or rash; or
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pain, redness, swelling, or irritation where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Warnings
Coagulation factor VIIa can cause severe or life-threatening side effects. Call your doctor at once if you have chest pain, shortness of breath, dizziness, pain, swelling, warmth in one leg, sudden numbness or weakness (especially on one side of the body), severe headache, slurred speech, problems with vision or balance.
Before taking this medicine
You should not receive coagulation factor VIIa if you are allergic to it.
Tell your doctor if you have or have ever had:
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coronary artery disease (clogged arteries);
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a heart attack or stroke;
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a severe injury or infection;
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if you are allergic to mouse, hamster, or cow proteins; or
It is not known if coagulation factor VIIa will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using coagulation factor VIIa.
How is coagulation factor VIIa given?
Coagulation factor VIIa is injected into a vein by a healthcare provider.
You may need medical tests to help determine how long you should use coagulation factor VIIa.
Wear a medical alert tag or carry an ID card to let others know you have a bleeding disorder in case of emergency. Tell any doctor who treats you that you are using coagulation factor VIIa.
Related/similar drugs
Idelvion, tranexamic acid, desmopressin, Hemgenix, Cyklokapron, DDAVP, Humate-P, Hemlibra, Beqvez, Hympavzi
What happens if I miss a dose?
In a medical setting you are not likely to miss a dose.
What happens if I overdose?
In a medical setting an overdose would be treated quickly.
What should I avoid after receiving coagulation factor VIIa?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
What other drugs will affect coagulation factor VIIa?
Tell your doctor about all your other medicines, especially, medications to treat or prevent bleeding episodes, such as:
This list is not complete. Other drugs may affect coagulation factor VIIa, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
More about coagulation factor viia
- Check interactions
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: miscellaneous coagulation modifiers
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Further information
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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