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Coagulation factor VIIa (injection)

Generic Name: coagulation factor VIIa (injection) (koe AG yoo LAY shun FAK tor)
Brand Name: NovoSeven RT with MixPro, NovoSeven, NovoSeven RT

Medically reviewed: January 24, 2017

What is coagulation factor VIIa?

Coagulation factor VIIa is a man-made protein similar to a natural protein in the body that helps the blood to clot.

Coagulation factor VIIa is used to treat or prevent bleeding in people with hemophilia A or hemophilia B, or factor VII deficiency.

Coagulation factor VIIa may also be used for purposes not listed in this medication guide.

Important Information

If possible before you receive coagulation factor VIIa, tell your doctor about all your medical conditions and allergies. Also make sure your doctor knows if you are pregnant or breast-feeding.

Call your doctor at once if you have sudden numbness or weakness, sudden cough or headache, pain or swelling in one or both legs, chest pain, or problems with vision, speech, or balance.

Before taking this medicine

You should not receive coagulation factor VIIa if you are allergic to it.

If possible before you receive coagulation factor VIIa, tell your doctor if you have:

In an emergency situation it may not be possible to tell your caregivers about your health conditions. Make sure any doctor caring for you afterward knows you have received this medicine.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

It is not known whether coagulation factor VIIa passes into breast milk or if it could harm a nursing baby. You should not breast-feed while receiving this medicine.

In an emergency situation it may not be possible to tell your caregivers if you are pregnant or breast feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received this medication.

How is coagulation factor VIIa given?

Coagulation factor VIIa is injected into a vein through an IV. A healthcare provider will give you this injection.

You may need frequent medical tests to help your doctor determine how long to treat you with coagulation factor VIIa.

Wear a medical alert tag or carry an ID card stating that you have a bleeding disorder in case of emergency. Any medical care provider who treats you should know that you are using coagulation factor VIIa.

What happens if I miss a dose?

Because you will receive coagulation factor VIIa in a clinical setting, you are not likely to miss a dose.

What happens if I overdose?

Because you will receive coagulation factor VIIa in a clinical setting, you are not likely to miss a dose.

What should I avoid after receiving coagulation factor VIIa?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Coagulation factor VIIa side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • sudden numbness or weakness, especially on one side of the body;

  • sudden severe headache, confusion, problems with vision, speech, or balance;

  • chest pain, sudden cough, wheezing, rapid breathing, coughing up blood;

  • pain, swelling, warmth, or redness in one or both legs;

  • fever;

  • little or no urinating;

  • a feeling that you might pass out; or

  • any bleeding that will not stop.

Common side effects may include:

  • mild headache;

  • joint pain;

  • nausea, vomiting;

  • swelling;

  • mild itching or rash; or

  • pain, redness, swelling, or irritation where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect coagulation factor VIIa?

Tell your doctor about all your current medicines and any you start or stop using, especially, medications to treat or prevent bleeding episodes, such as:

This list is not complete. Other drugs may interact with coagulation factor VIIa, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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