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Elitek

Generic Name: rasburicase (ras BUR ih kase)
Brand Name: Elitek

Medically reviewed by Drugs.com on Jul 9, 2018 – Written by Cerner Multum

What is Elitek?

Elitek helps keep uric acid levels in the body from getting too high. Uric acid levels can increase during cancer treatments when tumor cells break down.

Elitek is used to manage uric acid levels in adults and children receiving cancer treatment for leukemia, lymphoma, and certain tumors.

Elitek may also be used for purposes not listed in this medication guide.

Important Information

You should not receive Elitek if you have ever had an allergic reaction to it, or if you have a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency.

Get emergency medical help if you have signs of an allergic reaction: hives; wheezing, chest pain and tightness, difficult breathing; feeling light-headed; swelling of your face, lips, tongue, or throat.

Tell your caregivers or call your doctor at once if you have signs of a serious blood disorder--blue-colored skin or lips, headache, feeling weak or tired, trouble breathing, feeling like you might pass out, pounding heartbeats or fluttering in your chest.

Before taking this medicine

You should not receive Elitek if:

  • you have ever had an allergic reaction or blood cell problems after receiving Elitek; or

  • if you have an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD).

If you are of African or Mediterranean descent, your doctor may perform blood tests to make sure you do not have conditions that would prevent you from safely receiving Elitek.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether rasburicase passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

How is Elitek given?

Elitek is injected into a vein through an IV. A healthcare provider will give you this injection. This medicine must be given slowly, and the IV infusion can take at least 30 minutes to complete.

Elitek is usually given once per day for up to 5 days. Follow your doctor's dosing instructions very carefully.

While using Elitek, you may need frequent blood tests.

This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using Elitek.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your Elitek.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while receiving Elitek?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Elitek side effects

Get emergency medical help if you have signs of an allergic reaction: hives, rash; wheezing, chest pain and tightness, difficult breathing; feeling light-headed; swelling of your face, lips, tongue, or throat.

Your treatment with Elitek may be permanently discontinued if you have a serious allergic reaction.

Tell your caregivers or call your doctor at once if you have:

  • pale or yellowed skin, dark colored urine;

  • sores or white patches in or around your mouth, trouble swallowing or talking, dry mouth, bad breath, altered sense of taste;

  • fever, flu symptoms, rapid heart rate, rapid and shallow breathing, fainting; or

  • signs of a serious blood disorder--blue-colored skin or lips, headache, feeling weak or tired, trouble breathing, feeling like you might pass out, pounding heartbeats or fluttering in your chest.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Elitek?

Other drugs may interact with rasburicase, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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