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DigiFab

Generic Name: digoxin immune FAB (di JOX in im MYOON FAB)
Brand Name: DigiFab

Medically reviewed on July 5, 2017

What is DigiFab?

DigiFab is used as an antidote to treat a life-threatening overdose of digoxin or digitoxin.

DigiFab is not for treating a mild digitalis overdose.

DigiFab may also be used for purposes not listed in this medication guide.

Important Information

If possible, before you receive DigiFab, tell your doctor if you have heart disease or kidney disease, or if you are allergic to antibiotics or papaya extracts such as papain or chymopapain.

In an emergency situation it may not be possible to tell your caregivers about your health conditions. Make sure any doctor caring for you afterward knows you have received this medicine.

Before taking this medicine

If possible, before you receive DigiFab, tell your doctor if you have:

  • heart disease;

  • kidney disease;

  • if you are allergic to antibiotics; or

  • if you are allergic to papaya extracts such as papain or chymopapain (Chymodiactin).

FDA pregnancy category C. It is not known whether DigiFab will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether DigiFab passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

In an emergency situation it may not be possible to tell your caregivers if you are pregnant or breast feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received this medication.

How is digoxin immune FAB given?

DigiFab is injected into a vein through an IV. A healthcare provider will give you this injection.

You may need frequent medical tests to help your doctor determine how long to treat you with DigiFab.

This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using DigiFab.

What happens if I miss a dose?

Since DigiFab is given in an emergency situation by a healthcare professional, it is not likely that you will miss a dose.

What happens if I overdose?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid after receiving DigiFab?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

DigiFab side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • fever;

  • high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling);

  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling);

  • shortness of breath (even with mild exertion); or

  • swelling, rapid weight gain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect DigiFab?

Other drugs may interact with digoxin immune FAB, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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