Avacincaptad pegol ophthalmic

Generic name: avacincaptad pegol ophthalmic [ A-va-sin-KAP-tad-PEG-ol ]
Brand name: Izervay
Dosage form: intravitreal solution (2 mg/0.1 mL)
Drug class: Anti-angiogenic ophthalmic agents

Medically reviewed by Drugs.com on Nov 8, 2023. Written by Cerner Multum.

What is avacincaptad pegol ophthalmic?

Avacincaptad pegol ophthalmic (for the eye) is used to treat an eye condition called geographic atrophy in adults with age-related macular degeneration.

Avacincaptad pegol ophthalmic may also be used for purposes not listed in this medication guide.

Avacincaptad pegol ophthalmic side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Some side effects may occur right after the injection. Tell your doctor right away if you have:

• signs of eye infection--swelling, severe discomfort, crusting or drainage;

• severe eye redness or pain;

• eyes being more sensitive to light;

• blurred or cloudy vision; or

• changes in your vision, seeing flashes of light.

Common side effects of avacincaptad pegol ophthalmic may include:

• increased pressure inside the eye;

• blurred vision;

• an eye condition called neovascular age-related macular degeneration; or

• bleeding in the white part of the eye.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Related/similar drugs

Vabysmo, Eylea, Izervay, ranibizumab ophthalmic, Lucentis, aflibercept ophthalmic, Syfovre

Warnings

You should not receive avacincaptad pegol ophthalmic if you have swelling or infection in or around your eye.

Before taking this medicine

You should not receive avacincaptad pegol ophthalmic if you have swelling or infection in or around your eye.

Tell your doctor if you have ever had:

• increased pressure inside your eyes.

Tell your doctor if you are pregnant or breastfeeding.

How should I receive avacincaptad pegol ophthalmic?

Avacincaptad pegol ophthalmic is injected in your eye. A healthcare provider will give you this injection.

Your doctor will monitor the pressure inside your eye before and after giving you the injection.

Avacincaptad pegol ophthalmic is given once monthly.

You will need frequent vision exams before and after receiving avacincaptad pegol ophthalmic.

Avacincaptad pegol ophthalmic dosing information

Usual Adult Dose for Macular Degeneration:

2 mg (0.1 mL of 20 mg/mL solution) by intravitreal injection to each affected eye once monthly. Can be given approximately every 28 days plus or minus 7 days.

Duration of therapy: Up to 12 months.

Comments:
-Before the intravitreal injection, check the intraocular pressure (IOP).
-If necessary, ocular hypotensive medicine can be administered to reduce IOP.

Use: For the treatment of geographic atrophy (GA) secondary to age-related macular degeneration (AMD)

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your avacincaptad pegol ophthalmic injection.

What happens if I overdose?

In a medical setting an overdose would be treated quickly.

What should I avoid while receiving avacincaptad pegol ophthalmic?

avacincaptad pegol ophthalmic may cause blurred vision and may impair your reactions. Avoid driving or hazardous activity until you know how this medicine will affect you.

What other drugs will affect avacincaptad pegol ophthalmic?

Medicine used in the eyes is not likely to be affected by other drugs you use. But many drugs can interact. Tell your doctor about all your current medicines, including prescription and over-the-counter medicines, vitamins, and herbal products.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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