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Taking Ozempic: What foods should you avoid?

Medically reviewed by Leigh Ann Anderson, PharmD. Last updated on Jan 29, 2025.

Official Answer by Drugs.com

There are no specific foods you must avoid when taking Ozempic (generic name: semaglutide). You should avoid regular consumption of foods high in fat, sugar and calories. Ozempic works best if you combine it with a healthy diet and exercise plan as recommended by your healthcare provider for treatment for type 2 diabetes.

Ozempic can commonly cause stomach side effects, especially when you first start treatment. If you experience nausea or other stomach side effects while taking Ozempic, try:

Some of these items may also worsen your blood sugar control and slow down weight loss.

Side effects with Ozempic like nausea, vomiting, diarrhea, stomach pain or constipation are common. In most people, these effects usually lessen over time.

Your doctor may slowly increase your dose to help avoid these side effects. Higher doses of Ozempic may worsen stomach side effects.

Do you have to take Ozempic with food?

Ozempic can be taken with or without food. It is injected once per week subcutaneously (under the skin) of your stomach (abdomen), thigh, or upper arm, on the same day each week. You (or a caregiver) can inject at any time on that day.

Learn more: What is Ozempic used for and how does it work?

Related questions

What can I eat while taking Ozempic?

Treatment for type 2 diabetes involves following a healthy diet plan. Follow the specific diet plan given to you by your doctor or dietician. In general:

Your doctor may suggest that you see a registered dietitian to help learn about healthful food choices and meal planning, and address any poor food habits. Review the American Diabetes Association (ADA) website which may be useful for recipe and meal planning.

References

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How do Ozempic, Mounjaro, Wegovy, Zepbound compare for weight loss?

Ozempic, Mounjaro, Wegovy and Zepbound can all lead to long-term weight loss, but only Wegovy and Zepbound are approved by the FDA for this use. In studies, Zepbound has led to a 21% weight loss in adults using the highest dose, while Wegovy has led to about a 15% weight loss.

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How long does it take for Ozempic to work?

Your blood glucose (sugar) levels should start to fully decline within the first week after you start using Ozempic (semaglutide) at your regular dose. However, the full effect can take 8 weeks or longer, as this is a long-acting medication that is injected only once per week. Continue reading

Wegovy vs Ozempic: Which is Right for You?

Both Wegovy and Ozempic contain semaglutide, but Wegovy is prescribed for long-term weight management while Ozempic is used to control blood sugar levels in type 2 diabetes and help protect kidney function. They both lower the risk for heart-related complications, but they differ in other approved uses, doses, target populations and costs. Continue reading

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