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Can I take antibiotics with Mounjaro?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on April 16, 2025.

Official Answer by Drugs.com

You can generally take antibiotics while using Mounjaro (tirzepatide), but there are important considerations to keep in mind:

If you are prescribed oral antibiotics, your healthcare provider may monitor you more closely to ensure the antibiotic is working as expected. If you experience persistent symptoms of infection or side effects such as severe nausea, vomiting, or diarrhea (which can be caused by both Mounjaro and some antibiotics), contact your healthcare provider.

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Summary

Most people can safely take antibiotics with Mounjaro, but absorption of oral antibiotics may be reduced, especially when starting or increasing Mounjaro. Always consult your healthcare provider for personalized advice.

References

Mounjaro [package insert]. Updated 2025. Eli Lilly and Company. Accessed April 15, 2025 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d2d7da5d-ad07-4228-955f-cf7e355c8cc0

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