Is sleep apnea the hidden cause of your high blood pressure?
Yes, sleep apnea can cause high blood pressure. Each apnea episode causes oxygen levels in your blood to drop. In response, your brain triggers a stress reaction, releasing hormones that tighten blood vessels and increase heart rate. This can lead to higher blood pressure over time. Untreated sleep apnea increases the risk of heart disease and stroke.
How Does Sleep Apnea Affect Blood Pressure?
The connection between sleep apnea and high blood pressure (hypertension) is well established in medical research. Sleep apnea is often undiagnosed in patients with high blood pressure, making it a "hidden" cause that can go untreated. Resistant hypertension is commonly linked to untreated sleep apnea.
Some of the ways sleep apnea affects blood pressure include:
- Oxygen deprivation: Each apnea episode causes oxygen levels in your blood to drop, triggering a stress reaction. This causes your body to release hormones like adrenaline and cortisol. These hormones constrict blood vessels and increase heart rate, which can raise blood pressure.
- Sympathetic nervous system activation: The repeated drops in oxygen and brief awakenings keep your body’s “fight or flight” system on high alert, even during the day, resulting in persistently elevated blood pressure.
- Inflammation and vessel damage: Sleep apnea promotes inflammation and damages the lining of blood vessels, making it harder for them to relax and regulate blood pressure.
- Disrupted sleep patterns: Poor sleep quality from frequent awakenings can worsen metabolic health, contributing to weight gain and insulin resistance—both of which further raise blood pressure.
Is High Blood Pressure from Sleep Apnea Reversible?
High blood pressure caused by sleep apnea is often at least partially reversible when the sleep apnea is treated. The most widely studied and recommended therapy is continuous positive airway pressure (CPAP), which keeps the airway open during sleep and prevents the repeated drops in oxygen that drive up blood pressure in people with obstructive sleep apnea.
CPAP therapy has been shown in multiple clinical studies to significantly reduce both systolic and diastolic blood pressures in people with obstructive sleep apnea. Improvements can be seen within weeks to months of starting therapy, and the degree of blood pressure reduction is closely linked to how consistently the therapy is used.
Besides CPAP, other treatments such as oral appliances and weight loss can also contribute to lowering blood pressure by reducing the severity of sleep apnea.
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What Are the Signs You Should Be Tested for Sleep Apnea?
Sleep apnea often goes undiagnosed because many symptoms occur during sleep, but certain warning signs are strong indicators that you should seek medical advice:
- Loud, frequent snoring
- Waking up gasping for air
- Daytime fatigue despite enough sleep
- Morning headaches
- High blood pressure that doesn’t improve with medication
How Is Sleep Apnea Treated to Help Lower Blood Pressure?
Sleep apnea treatment, particularly with continuous positive airway pressure (CPAP), is a proven strategy for lowering blood pressure in people with obstructive sleep apnea (OSA). There are several treatment strategies for sleep apnea, which can also help reduce blood pressure.
Continuous Positive Airway Pressure (CPAP)
CPAP therapy is the gold standard for treating OSA. It delivers a steady stream of air through a mask, keeping the airway open during sleep and preventing the breathing interruptions that trigger spikes in blood pressure. Numerous studies and meta-analyses show that CPAP therapy leads to significant reductions in both systolic and diastolic blood pressure, especially in people with uncontrolled or resistant hypertension. Consistency with therapy is key for optimal results.
Weight loss and Lifestyle Changes
Being overweight causes sleep apnea primarily by increasing fat around the airway and abdomen, which physically narrows the airway and impairs breathing during sleep. Losing weight can reduce the severity of OSA and further help lower blood pressure.
Oral Appliances
Certain devices can reposition the jaw or tongue, and can be effective for mild to moderate OSA.
Surgical Options
In selected cases, surgical procedures to remove airway obstructions may be considered.
Follow-up sleep studies and blood pressure monitoring is essential during sleep apnea treatment. Your healthcare provider can discuss different treatment options with you and help you determine the best option for you.
Conclusion
Sleep apnea is a common but often hidden cause of high blood pressure. It contributes to hypertension through multiple mechanisms and is especially prevalent in people whose blood pressure is difficult to control. Left untreated, high blood pressure can lead to many serious complications. Identifying and treating sleep apnea can lead to significant improvements in blood pressure and overall cardiovascular health. Speak with a healthcare provider if any symptoms of sleep apnea or unexplained high blood pressure are present.
References
- Brown, J., et. al. 2022. Obstructive Sleep Apnea and Hypertension: Updates to a Critical Relationship. Current hypertension reports, 24(6), 173–184. https://doi.org/10.1007/s11906-022-01181-w
- Kapa, S., et. al. 2008. Sleep apnea and hypertension: interactions and implications for management. Hypertension (Dallas, Tex. : 1979), 51(3), 605–608. https://doi.org/10.1161/HYPERTENSIONAHA.106.076190
- Lui, M. M., et. al. 2021. Continuous positive airway pressure improves blood pressure and serum cardiovascular biomarkers in obstructive sleep apnoea and hypertension. The European respiratory journal, 58(5), 2003687. https://doi.org/10.1183/13993003.03687-2020
- Martínez-García, M. A., et. al. 2013. Effect of CPAP on blood pressure in patients with obstructive sleep apnea and resistant hypertension: the HIPARCO randomized clinical trial. JAMA, 310(22), 2407–2415. https://doi.org/10.1001/jama.2013.281250
- Shafazand, S., et. al. 2014. Effect of CPAP on blood pressure in patients with obstructive sleep apnea and resistant hypertension. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 10(3), 341–343. https://doi.org/10.5664/jcsm.3554
- Tobushi, T., et. al. 2024. Sleep Apnea, Autonomic Disturbances, and Blood Pressure Variability. In: Hypertension. DOI: https://doi.org/10.1161/HYPERTENSIONAHA.124.20433
- Trakada, G., et. al. 2007. Sleep Apnea and its association with the Stress System, Inflammation, Insulin Resistance and Visceral Obesity. Sleep Medicine Clinics, 2(2), 251–261. https://doi.org/10.1016/j.jsmc.2007.04.003
- Wang, X., et. al. 2022. Continuous positive airway pressure may improve hypertension in patients with obstructive sleep apnea-hypopnea syndrome by inhibiting inflammation and oxidative stress. Archives of medical science : AMS, 19(1), 237–241. https://doi.org/10.5114/aoms/156490
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