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Does Menopur need to be refrigerated?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on Aug 27, 2025.

Official Answer by Drugs.com

Menopur does not require refrigeration before mixing, but proper storage is essential to maintain its safety and effectiveness. The storage needs differ for unmixed vials versus the reconstituted (mixed) solution. Below, we will review the recommended storage instructions for Menopur.

Storage Instructions for Unmixed Menopur

Unmixed Menopur vials should be stored at controlled room temperature (ideally up to 25°C (77°F)) or in the refrigerator. Always keep the vials in their original packaging to shield them from light, which can degrade the medication's effectiveness. A home medicine cabinet located away from sources of heat, humidity, and direct sunlight is safe for storage.

Storage After Reconstitution (Mixing)

After Menopur is reconstituted (mixed with sterile diluent), it should typically be used immediately for maximum safety and efficacy. Contact your healthcare provider if you have questions about whether it is safe to take Menopur after it has been mixed. Any unused mixed Menopur should be thrown away and not saved for a later dose.

Final Storage Safety Tips

Always follow the instructions given by a fertility clinic or prescribing physician, as recommendations could occasionally vary depending on local protocols or patient needs. Never use Menopur if it is expired, or if there are signs it has been improperly stored—for example, exposure to temperature extremes, light, or moisture. To ensure safety, keep Menopur and all related supplies out of reach of children and securely stored to prevent accidental exposure.

This is not all the information you need to know about Menopur for safe and effective use and does not take the place of your doctor’s directions. Review the full patient medication guide and discuss this information and any questions you have with your doctor or other health care provider.

References
  1. Menopur [package insert]. Updated November 2024. Ferring Pharmaceuticals Inc. Accessed on August 27, 2025 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=22c8db95-c3db-1770-8086-31356fbabe35

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