Can Kisunla be used with other Alzheimer's drugs?
Yes, Kisunla (donanemab-azbt) can be used with other Alzheimer’s drugs. Clinical trials of Kisunla that led to its FDA approval included both people with Alzheimer’s disease who were taking other treatments and people who were not.
Other medications that were taken in addition to Kisunla for Alzheimer’s disease during studies included acetylcholinesterase inhibitors, like donepezil (Aricept), and NMDA antagonists, such as memantine (Namenda). All of these medications work differently to help treat Alzheimer’s disease, and taking them together can be beneficial for some.
Kisunla does not have any known drug interactions, but you should still share a list of your current medications with your healthcare provider. They can check whether your current medications are working well for you and that they are not causing side effects.
This is not all the information you need to know about Kisunla (donanemab-azbt) for safe and effective use and does not take the place of your doctor’s directions. Review the full product information and discuss this information and any questions you have with your doctor or other health care provider.
References
Guo, J., et. al. 2020. Memantine, Donepezil, or Combination Therapy—What is the best therapy for Alzheimer’s Disease? A Network Meta‐Analysis. In: Brain and Behavior. DOI: https://doi.org/10.1002%2Fbrb3.1831
Kisunla [package insert]. July 2024. Eli Lilly and Company. Accessed September 27, 2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=190352d4-ef62-4679-b4fa-e846e2766afa
Read next
How do I decide between Leqembi and Kisunla?
Leqembi (lecanemab-irmb) and Kisunla (donanemab-azbt) are two injectable treatments for Alzheimer’s disease. While both medications work by reducing amyloid plaques in the brain, there are some differences to consider when deciding between the two. These include effectiveness, side effects, and cost. Continue reading
Will insurance cover Kisunla treatment?
Kisunla treatment typically requires a prior authorization approval from your commercial insurance company before they will pay for it. Medicare Part B may pay for Kisunla and brain imaging scans if you are eligible, but you must first meet your yearly deductible and then pay coinsurance costs, which are usually 20%. Continue reading
How well does Kisunla work?
In studies, treatment with Kisunla significantly slowed Alzheimer's disease clinical decline when compared to a group who received a placebo. People with the least advanced disease experienced the strongest outcomes, with a 35% slowing of decline on the iADRS score, which measures memory, thinking, and daily functioning. Continue reading
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Drug information
- Kisunla Information for Consumers
- Kisunla prescribing info & package insert (for Health Professionals)
- Side Effects of Kisunla (detailed)
Related support groups
- Kisunla (6 questions, 3 members)
- Alzheimer's Disease (36 questions, 99 members)