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How many doses of Arexvy are required?

Medically reviewed by Carmen Pope, Senior Medical Editor, B. Pharm. Last updated on April 30, 2026.

Official Answer by Drugs.com

Just one dose of Arexvy is recommended. Arexvy is a single-shot vaccine given into the upper arm muscle. It protects against lower respiratory tract disease (LRTD) caused by the respiratory syncytial virus (RSV).

Who is it for?

Arexvy is approved for adults 60 and older, and for adults aged 18–59 who face a higher risk due to chronic conditions such as heart disease, lung disease, diabetes, or kidney or liver disease.

When to get it?

RSV season typically begins in October in the U.S., so getting vaccinated before then is recommended. Arexvy can safely be given at the same time as a flu shot.

How often?

It's not yet clear whether Arexvy will need to be repeated annually. Unlike influenza and COVID-19, RSV doesn't mutate rapidly, so the vaccine shouldn't need frequent updates. Clinical trials showed protection lasting through two to three RSV seasons, suggesting it may only be needed every two to three years, but ongoing research will clarify this.

References

Read next

What is the difference between Arexvy and Abrysvo?

Arexvy and Abrysvo are both RSV vaccines that are approved for use in adults over the age of 60 to reduce their risk of developing lower respiratory tract disease (LRTD). They are also approved for adults aged 18 through 59 years with certain chronic medical conditions (such as chronic pulmonary disease, chronic cardiovascular disease, diabetes, chronic kidney or liver disease) that put them at increased risk of LRTD caused by RSV. Abrysvo is also approved for use in pregnant women between 32 through 36 weeks gestation, to protect infants against LRTD from the moment they are born until they are 6 months of age. Arexvy is made by GSK and was approved on May 3, 2023; the first RSV vaccine to be approved for older adults. Abrysvo is made by Pfizer and was approved on May 31, 2023; the second RSV vaccine to be approved for older adults. Continue reading

RSV symptoms - What are they?

Respiratory syncytial virus (RSV) symptoms include a runny nose, sore throat, stuffy nose, cough, wheezing, headache, and fever, with most people recovering after 1 to 2 weeks. In very young infants, respiratory syncytial virus (RSV) symptoms may include decreased activity, irritability, and breathing difficulties. RSV symptoms can become severe in some infants and older adults and may require hospitalization. Continue reading

Is Arexvy a live vaccine?

Arexvy is not a live vaccine it is a recombinant subunit RSV vaccine that does not contain any live virus. Continue reading

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