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How is Empaveli administered?

Medically reviewed by Carmen Fookes, BPharm. Last updated on Sep 8, 2021.

Official answer

by Drugs.com

Empaveli is given subcutaneously (this means under the skin) using an infusion pump, into a clear area of skin on your stomach (avoid around the belly button), top of the thighs, hips, or upper arms. Your doctor or nurse will show you how to do this so you can administer it at home, or a caregiver can administer it to you. Empaveli is usually given twice a week, although a healthcare provider may instruct some people to infuse it every three days. It usually takes around 30 minutes to infuse (if using two infusion sites) or approximately 60 minutes (if using one infusion site). See the product information for complete details about the administration process.

Empaveli is a prescription medicine used to treat adults with a disease called paroxysmal nocturnal hemoglobinuria (PNH). PNH is a rare acquired, life-threatening disease of the blood that is characterized by the destruction of red blood cells (hemolytic anemia), blood clots (thrombosis), and impaired bone marrow function. Empaveli is the first and only medicine approved for PNH.


References
  • Empaveli (pegcetacoplan) Updated 07/2021. Apellis Pharmaceuticals, Inc. https://www.drugs.com/pro/empaveli.html
  • Paroxysmal Nocturnal Hemoglobinuria (PNH) The Sidney Kimmel Comprehensive Cancer Center. John Hopkins Medicine. https://www.hopkinsmedicine.org/kimmel_cancer_center/types_cancer/paroxysmal_nocturnal_hemoglobinuria_PNH.html#:~:text=Paroxysmal%20nocturnal%20hemoglobinuria%20(PNH)%20is,of%20the%20three%20blood%20components).

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