Does Auvelity cause weight gain or loss?
Weight gain has not been reported with Auvelity, but in one 6-week study, participants lost, on average, half a pound, while those taking placebo gained about one pound. Animal studies have also reported that the administration of dextromethorphan/bupropion did not affect body weight, weight gain, or food consumption.
References
- Auvelity Prescribing Information. https://www.axsome.com/auvelity-prescribing-information.pdf
- Auvelity FAQs. https://www.auvelity.com/resources#faq
Read next
Does Auvelity work better than Wellbutrin?
Auvelity worked significantly better than Wellbutrin (bupropion) at relieving symptoms of depression in a small randomized double-blind, parallel trial that lasted for 6 weeks. It also had a faster onset of effect, with improvement in the Montgomery-Åsberg Depression Rating Scale (MADRS) score being observed as early as week 1 and differences being statistically significant by week 2. Continue reading
Auvelity vs. Wellbutrin: Effectiveness for Depression?
Both Auvelity and Wellbutrin are effective for depression but a small RCT (n=80) reported that Auvelity worked significantly better than Wellbutrin and took less time to start working. 43 people prescribed Auvelity experienced an overall decrease in their Montgomery-Åsberg Depression Rating Scale (MADRS) score of 13.7 points after 6 weeks compared to a decrease of 8.8 points in the 37 people prescribed bupropion (least-squares mean difference=-4.9; 95% CI=-3.1, -6.8). Continue reading
What makes Auvelity different from other antidepressants?
Auvelity is a combination oral tablet for depression containing dextromethorphan and bupropion that works differently from other antidepressants because it has a direct effect on the N-methyl-D-aspartate (NMDA) receptor as well as possibly other traditional neurotransmitter effects. It also works much faster than traditional antidepressants, and it does appear to be more effective. Continue reading
See also:
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