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In the US, Sirolimus (sirolimus systemic) is a member of the following drug classes: mTOR inhibitors, selective immunosuppressants and is used to treat Lymphangioleiomyomatosis and Organ Transplant - Rejection Prophylaxis.

US matches:



ATC (Anatomical Therapeutic Chemical Classification)


CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Category

Selective immunosuppressant

Chemical Names

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-metoxycyclohexyl]-1-metyletyl]-10,21-dime (WHO)

(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-{(1R)-2-[(1S,3R,4R)-4-hydroxy-3-metoxycyclohexyl]-1-metyletyl}-10,2 (IUPAC)

Foreign Names

  • Sirolimusum (Latin)
  • Sirolimus (German)
  • Sirolimus (French)
  • Sirolimus (Spanish)

Generic Names

  • Sirolimus (OS: BAN, USAN, DCF)
  • AY-22989 (IS: Wyeth)
  • NSC-226080 (IS)
  • NSC-606698 (IS)
  • Rapamune (IS)
  • Rapamycin (IS)
  • WY-090217 (IS: Wyeth)

Brand Names

  • Rapacan
    Biocon, India
  • Rapamune
    Astellas, South Korea; Patheon, Israel; Pfizer, Argentina; Pfizer, Austria; Pfizer, Australia; Pfizer, Belgium; Pfizer, Canada; Pfizer, Switzerland; Pfizer, Czech Republic; Pfizer, Germany; Pfizer, Denmark; Pfizer, Ecuador; Pfizer, Egypt; Pfizer, Spain; Pfizer, Finland; Pfizer, France; Pfizer, United Kingdom; Pfizer, Greece; Pfizer, Hong Kong; Pfizer, Croatia (Hrvatska); Pfizer, Hungary; Pfizer, Ireland; Pfizer, Iceland; Pfizer, Malaysia; Pfizer, Netherlands; Pfizer, Norway; Pfizer, New Zealand; Pfizer, Philippines; Pfizer, Poland; Pfizer, Portugal; Pfizer, Serbia; Pfizer, Sweden; Pfizer, Singapore; Pfizer, Slovakia; Pfizer, Tunisia; Pfizer, Turkey; Pfizer, Taiwan; Pfizer, South Africa; Pfizer Italia, Italy; Wyeth, Brazil; Wyeth, Chile; Wyeth, Greece; Wyeth, Latvia; Wyeth, Oman; Wyeth, Romania; Wyeth, Serbia; Wyeth, Tunisia; Wyeth Medica, Lithuania; Wyeth Pharmaceutical Co Ltd, China; Wyeth, Inc., United States
  • Rui Pa Ming
    Kerui Pharmaceutical, China
  • Saimosi
    Huadong Pharmaceutical Group, China
  • Sirotan
    Complex Therapeutics, Chile
  • Yixinke
    NCPC GeneTech, China


BANBritish Approved Name
DCFDénomination Commune Française
IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.