Drug Interaction Report
2 potential interactions and/or warnings found for the following 2 drugs:
- Igalmi (dexmedetomidine)
- landiolol
Interactions between your drugs
dexmedeTOMIDine landiolol
Applies to: Igalmi (dexmedetomidine), landiolol
Consumer information for this interaction is not currently available.
MONITOR: Dexmedetomidine has been associated with hypotensive and negative chronotropic effects. Coadministration with other agents causing these effects, especially vasodilators and alpha-2 agonists, may result in additive effects on blood pressure and heart rate. Data have been conflicting. Additive pharmacodynamic effects were not observed in some clinical studies.
MANAGEMENT: Caution and monitoring of the patient's hemodynamic status are recommended during coadministration.
Drug and food interactions
dexmedeTOMIDine food
Applies to: Igalmi (dexmedetomidine)
Alcohol can increase the nervous system side effects of dexmedeTOMIDine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with dexmedeTOMIDine. Do not use more than the recommended dose of dexmedeTOMIDine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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