Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- delavirdine
- sodium bicarbonate / sodium citrate
Interactions between your drugs
sodium bicarbonate delavirdine
Applies to: sodium bicarbonate / sodium citrate, delavirdine
ADJUST DOSING INTERVAL: Aluminum and magnesium containing antacids have been reported to decrease the bioavailability of delavirdine by an average of 41%. The mechanism may be related to decreased absorption of delavirdine. Other antacids may also interact.
MANAGEMENT: Delavirdine administration should be separated by at least 1 hour from one of these preparations.
References (1)
- (2001) "Product Information. Rescriptor (delavirdine)." Pharmacia and Upjohn
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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