Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- colesevelam
- maralixibat
Interactions between your drugs
colesevelam maralixibat
Applies to: colesevelam, maralixibat
ADJUST DOSING INTERVAL: Bile-acid sequestrants such as cholestyramine, colestipol, and colesevelam may bind to maralixibat in the gut and diminish its therapeutic effects.
MANAGEMENT: Bile-acid binding resins such as cholestyramine, colestipol, and colesevelam should be administered at least 4 hours before or 4 hours after administration of maralixibat.
References (1)
- (2021) "Product Information. Livmarli (maralixibat)." Mirum Pharmaceuticals, Inc.
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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