Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- Milophene (clomiphene)
- ospemifene
Interactions between your drugs
clomiPHENE ospemifene
Applies to: Milophene (clomiphene), ospemifene
Talk to your doctor before using ospemifene together with clomiPHENE. Both medications may have similar effects on certain tissues in the body. Therefore, combining them may increase the risk of side effects such as blood clots, stroke, and some cancers. You should seek immediate medical attention if you experience chest pain, shortness of breath, and/or pain or swelling in the arms or legs during treatment with either medication. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
ospemifene food
Applies to: ospemifene
Food significantly increases the absorption of ospemifene. You should take ospemifene with a meal, preferably at the same time each day. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
Selective estrogen receptor modulators
Therapeutic duplication
The recommended maximum number of medicines in the 'selective estrogen receptor modulators' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'selective estrogen receptor modulators' category:
- Milophene (clomiphene)
- ospemifene
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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