Drug Interaction Report

Ritonavir may interfere with the process used to make atidarsagene autotemcel from your own blood cells. The makers of atidarsagene autotemcel recommend that ritonavir be stopped before your blood stem cells are collected. You should speak with your doctor to ensure that ritonavir is stopped at the appropriate time. Atidarsagene autotemcel may also interfere with the results of certain types of laboratory tests. Be sure to speak with the laboratory or your healthcare provider if you need to be screened for certain types of viruses, like human immunodeficiency virus (HIV), to ensure that treatment with atidarsagene autotemcel does not interfere with the test. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Lopinavir may interfere with the process used to make atidarsagene autotemcel from your own blood cells. The makers of atidarsagene autotemcel recommend that lopinavir be stopped before your blood stem cells are collected. You should speak with your doctor to ensure that lopinavir is stopped at the appropriate time. Atidarsagene autotemcel may also interfere with the results of certain types of laboratory tests. Be sure to speak with the laboratory or your healthcare provider if you need to be screened for certain types of viruses, like human immunodeficiency virus (HIV), to ensure that treatment with atidarsagene autotemcel does not interfere with the test. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Tenofovir may interfere with the process used to make atidarsagene autotemcel from your own blood cells. The makers of atidarsagene autotemcel recommend that tenofovir be stopped before your blood stem cells are collected. You should speak with your doctor to ensure that tenofovir is stopped at the appropriate time. Atidarsagene autotemcel may also interfere with the results of certain types of laboratory tests. Be sure to speak with the laboratory or your healthcare provider if you need to be screened for certain types of viruses, like human immunodeficiency virus (HIV), to ensure that treatment with atidarsagene autotemcel does not interfere with the test. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Emtricitabine may interfere with the process used to make atidarsagene autotemcel from your own blood cells. The makers of atidarsagene autotemcel recommend that emtricitabine be stopped before your blood stem cells are collected. You should speak with your doctor to ensure that emtricitabine is stopped at the appropriate time. Atidarsagene autotemcel may also interfere with the results of certain types of laboratory tests. Be sure to speak with the laboratory or your healthcare provider if you need to be screened for certain types of viruses, like human immunodeficiency virus (HIV), to ensure that treatment with atidarsagene autotemcel does not interfere with the test. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Ritonavir may increase the blood levels and effects of tenofovir. This can increase the risk of side effects including serious ones like kidney or liver damage and a condition known as lactic acidosis, which is a buildup of lactic acid in the blood. You should seek immediate medical attention if you develop symptoms of these conditions. Symptoms of kidney damage may include swelling, weight gain, shortness of breath, drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea, vomiting, pain in your lower back, and urinating more or less than usual or not at all. Symptoms of liver damage may include fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Symptoms of lactic acidosis may include fatigue, unusual muscle pain, difficulty breathing, stomach pain, nausea, vomiting, lightheadedness, dizziness, and a fast or irregular heartbeat. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Lopinavir may increase the blood levels and effects of tenofovir. This can increase the risk of side effects including serious ones like kidney or liver damage and a condition known as lactic acidosis, which is a buildup of lactic acid in the blood. You should seek immediate medical attention if you develop symptoms of these conditions. Symptoms of kidney damage may include swelling, weight gain, shortness of breath, drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea, vomiting, pain in your lower back, and urinating more or less than usual or not at all. Symptoms of liver damage may include fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Symptoms of lactic acidosis may include fatigue, unusual muscle pain, difficulty breathing, stomach pain, nausea, vomiting, lightheadedness, dizziness, and a fast or irregular heartbeat. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Ritonavir should be taken with food to lessen gastrointestinal side effects. It is important that you take this medication exactly as prescribed by your doctor. Do not change your treatment or stop treatment without first talking to your doctor.

Food may affect the absorption of lopinavir-ritonavir (brand name Kaletra) depending on whether you are taking the oral solution or the tablet. The oral solution should be taken with food to enhance absorption and help it work better. The tablet formulation can be take with or without food. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Information for this minor interaction is available on the professional version.