Drug Interaction Report

Voxelotor may increase the blood levels of elacestrant. This may increase the risk of side effects such as muscle pain, nausea, increased cholesterol, increased liver enzymes, fatigue, decreased hemoglobin, and vomiting. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Elacestrant should be taken with food at approximately the same time each day. Grapefruit, grapefruit juice, and supplements that contain grapefruit, however, may increase the blood levels of elacestrant, which may increase the risk of side effects such as muscle pain, nausea, increased cholesterol, increased liver enzymes, fatigue, decreased hemoglobin, and vomiting. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Grapefruit juice may increase the blood levels of certain medications such as voxelotor. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with voxelotor. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.