Drug Interaction Report

Tirzepatide may affect the blood levels and effects of oral contraceptives, which contain hormones such as estradiol. This may increase the risk of breakthrough bleeding and unintended pregnancy. Alternative, non-oral methods of birth control should be used, or add another method of birth control (such as condoms) to the oral contraceptive for 4 weeks after starting tirzepatide and for 4 weeks each time after the dose of tirzepatide is increased to avoid unintended pregnancy. Talk to your gynecologist or other healthcare professional if you have any questions or concerns, and for help in selecting an effective method of birth control that is best for you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Tirzepatide may affect the absorption of other medications that you take by mouth. In some cases, this may affect how well and/or how fast those medications work, or it may make no difference. Talk to a healthcare provider if you have any questions or concerns, and contact your doctor if your symptoms worsen or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Information for this minor interaction is available on the professional version.