Drug Interaction Report
1 potential interaction and/or warning found for the following 2 drugs:
- dorzolamide / latanoprost / timolol ophthalmic
- fluorescein
Interactions between your drugs
timolol ophthalmic fluorescein
Applies to: dorzolamide / latanoprost / timolol ophthalmic, fluorescein
MONITOR: Beta-adrenergic blockers (including ophthalmic formulations) and ACE inhibitors may increase the severity and duration of acute anaphylactic reactions to fluorescein injection. In addition, anaphylaxis may be resistant to the usual treatment modalities. The mechanism is unknown.
MANAGEMENT: Patients should be closely monitored for signs of severe, acute hypersensitivity reactions during fluorescein injection, and facilities and equipment for resuscitation, cardiovascular support, and airway management should be immediately available. Clinicians should be aware that larger doses of epinephrine or other adrenergic agents may be required.
References (1)
- (2006) "Product Information. AK-Fluor (fluorescein)." Akorn Inc
Drug and food interactions
No alcohol/food interactions were found with the drugs in your list. However, this does not necessarily mean no food interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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