Drug Interaction Report
3 potential interactions and/or warnings found for the following 2 drugs:
- Lonsurf (tipiracil / trifluridine)
- pembrolizumab
Interactions between your drugs
pembrolizumab trifluridine
Applies to: pembrolizumab, Lonsurf (tipiracil / trifluridine)
Using trifluridine may decrease the effects of pembrolizumab, which may make the medication less effective in treating your condition. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact or may choose to postpone treatment with pembrolizumab. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
pembrolizumab tipiracil
Applies to: pembrolizumab, Lonsurf (tipiracil / trifluridine)
Using tipiracil may decrease the effects of pembrolizumab, which may make the medication less effective in treating your condition. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact or may choose to postpone treatment with pembrolizumab. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
trifluridine food
Applies to: Lonsurf (tipiracil / trifluridine)
Trifluridine should be taken within one hour after eating your morning or evening meals. This may help to reduce the medication's harmful effects on white blood cells. Talk to you doctor or pharmacist if you have any questions or concerns.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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